ABSTRACT
Seizures may occur in close relation to surgical procedures or with the use of anesthetic agents in several situations. Thecausative factors include an interruption of treatment with antiepileptic drugs (AEDs) or inadequate blood concentrations resultingfrom impaired gastrointestinal absorption. In operative procedures not involving the brain, transient seizures can arise frommetabolic derangements or drug neurotoxicity. Other causes include hypoxia, hypotension, and embolic infarction. Seizuresoccurring shortly after injection of moderate to large amounts of local anesthetic should raise the suspicion of inadvertentintravenous injection. Seizures may also indicate withdrawal from unsuspected chronic use of excessive amounts of alcohol,sedative medications, mood-stabilizing agents, or AEDs. Rarely, sleep deprivation and drugs like flumazenil may precipitateseizures. We discuss the management of status epilepticus following laparoscopic urology procedure in a patient of chronickidney disease with a history of the previous craniotomy.