ABSTRACT
Ultrasound guided fine needle aspiration biopsy of abdominal masses. Material Methods: 200 patients with abdominal lump were subjected to fine needle aspiration biopsy by a 20-22 G needle and smears prepared were stained with H & E and Papanicolaou stains. Histopathological specimens were processed and stained with H & E stain and a cytohistological correlative study performed. 128 (74%) were females and 72 (36%) were males. 83 cases (41.5%) had a mass in the hepatobiliary region, out of which 53 (63.9%) had a mass in the gall bladder. Malignant lesion constituted the commonest cytologic diagnostic category 115 cases (57.5%). Adenocarcinoma gall bladder was found in 31 cases (37.3%) followed by metastatic adenocarcinoma liver in 12 cases (14.5%) and hepatocellular carcinoma in 8 cases (9.6%). Adenocarcinoma stomach 8 cases (18.6%) was the commonest GI malignancy followed by adenocarcinoma intestine 7 cases (16.3%). Serous cystadenocarcinoma comprised the commonest ovarian cancer, 5 cases (12.5%) followed by mucinous cystadenocarcinoma, 2 cases (5.1%). Overall sensitivity of 94.11%, specificity of 100% and diagnostic accuracy of 95.7% was found in the present cytohistological correlative study.
ABSTRACT
Gleason's tumour grade has been accepted as a benchmark protocol in qualifying prostate cancer on histology. Since cyto-evaluation of suspected prostatic malignancy is being increasingly accepted, we have attempted a correlation between cytologic smear pattern categories and Gleason's grade, accorded on cytologic and histologic material and obtained from the same patient, simultaneously in 60 patients. The cytologic smears were classified as 1 well differentiated, corresponding to combined Gleason score 2-4, II moderately differentiated, Gleason 5-7, and III poorly differentiated, corresponding to Gleason 8-10. An overall concordance of 89% was observed between grading on cytologic and histologic material. The incidence of metastases and progression of clinical stage were also found to be clearly influenced by the cytologically accorded grade