ABSTRACT
Cervical cancer constitutes a major health problem in developing countries like Bolivia. The roles of certain genotypes of human papillomaviruses (HPVs) in the pathogenesis of cervical cancer is well established. The prevalence of HPV infection among sexually active women varies greatly. Information regarding HPV infection in Bolivia is very much scarce, specially in regions like the Amazonian lowland. We studied 135 healthy women living in four rural localities of the Bolivian Amazon. Presence of HPV in DNA extracted from cervical swabs was analyzed using a reverse line hybridization assay. The estimated overall HPV infection prevalence among the studied rural localities was 5.9 percent (ranging from 0-16.6 percent). These values were unexpectedly low considering Bolivia has a high incidence of cervical cancer. The fact that Amazonian people seem to be less exposed to HPV, makes it likely that some other risk factors including host lifestyle behaviors and genetic background may be involved in the development of cervical cancer in this population
Subject(s)
Adolescent , Humans , Female , Adult , Middle Aged , Papillomaviridae , Papillomavirus Infections , Tumor Virus Infections , Bolivia , DNA, Viral , Nucleic Acid Hybridization , Papillomavirus Infections , Polymerase Chain Reaction , Population Surveillance , Prevalence , Risk Factors , Tumor Virus Infections , Vaginal SmearsABSTRACT
Este instrumento, el manual de bioseguridad para el personal de salud, tiene como objetivos principales el de proteger al enfermo de infecciones sobrecargadas; proteger al personal de salud de infectarse o diseminar la infección intrainstitucionalmente, está comprobado que un gran número de infecciones pueden transmitirse por la sangre o al manejar fluidos orgánicos como ocurre con el VIH y el VHB. Por lo tanto las vías posibles de transmisión accidental pueden ser: del paciente al profesional, entre pacientes o del profesional al paciente