ABSTRACT
The early monitoring, detection and treatment of the myocardial damage caused by chemotherapeutic drugs have important significances in avoiding further damage to cardiac structure and function and improve the prognosis of patients. Imaging methods have played an important role in the evaluation of myocardial damage caused by chemotherapeutic drugs. The advancements of imaging techniques in monitoring the myocardial damage caused by chemotherapeutic drugs were reviewed in this article.
ABSTRACT
Objective To observe the value of 18F-FDG PET/CT in diagnosis of malignant tumors in biliary system. Methods A retrospective study of 18F-FDG PET/CT imaging feature was performed on 34 patients with clinical suspicion of biliary system malignancy. Pathological results of 18 lymph nodes were obtained in 12 patients after surgical operation or needle biopsy. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 18F-FDG PET/CT for detecting primary focus of malignant tumor and lymph node metastasis were obtained. Lymph nodes in 12 patients were examined by surgical or biopsy pathology. Results In 34 patients, there were 31 with malignant lesions and 3 with benign lesions. The sensitivity, specificity, PPV, NPV and accuracy of 18F-FDG PET/CT for detecting primary focus was 100% (31/31), 66.67% (2/3), 96.88% (31/32), 100% (2/2) and 97.06% (33/34), respectively. The maximum standardized uptake value (SUVmax) of primary focus of malignant tumors was 8.42±4.27, while of 3 cases with benign lesions was 12.90, 2.00 and 1.90, respectively. Pathological results were obtained in 18 lymph nodes, including 13 benign nodes and 5 malignant nodes. The sensitivity, specificity, PPV, NPV and accuracy of 18F-FDG PET/CT for diagnosing lymph node metastasis was 76.92% (10/13), 60.00% (3/5), 83.33% (10/12), 50.00% (3/6) and 72.22% (13/18), respectively. Conclusion PET/CT has important value in diagnosis of malignant tumors in biliary system.