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Pakistan Journal of Pharmaceutical Sciences. 2015; 28 (3): 875-879
in English | IMEMR | ID: emr-191713

ABSTRACT

Coronary artery disease [CAD] is a leading cause of mortality in the developing countries. The aim of the study was to check the association of Myocardial infarction [MI] with several factors such as smoking and smoking exposure, blood pressure, sugar and cholesterol level, stress, anxiety and lifestyle. A cross sectional community based survey was conducted involving 469 patients having one or more risk factors or having complains regarding MI and already diagnosed MI, was taken using Multistage sampling technique from Sheikh Zaid Hospital and Abbas Institute of Medical Sciences. The Chi-square test was used to check the association of different risk factors with myocardial infarction. The multivariate Logistic regression model was also applied to find out the most significant risk factors of MI.The results revealed that MI was strongly associated with following risk factors family size [p=0.04], profession of respondent [p=0.026], smoking [p=0.028] and smoking exposure [p=0.043]. The finding also showed significant association of MI in study population with diastolic blood pressure [p=0.03], cholesterol [p=0.047], blood sugar [p=0.008], stress [p=0.036], anxiety [p=0.044] and lifestyle [p=0.015]. The study revealed that family size, family history, smoking and its smoking exposure, cholesterol, blood sugar, diastolic blood pressure, stress and anxiety are the major contributing risk factors of MI in the community, whereas age and gender elucidated minor contributions in the development of MI.

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