ABSTRACT
Purpose - To study the spontaneous variability of single (VPCs) and coupled (CVPCs) in patients with chronic Chagas' disease (CCD). Patients and Methods - Twenty patients with CCD, 14 male, in class I and III NYHA, with frequent VPCs and VCPCs, free of drug therapy were studied.21 hour Holter monitoring was done for 4 subsequent days. The data analysis assessed the variation in the frequency of VPCs and CVPCs between patients, seven hour periods one hour periods in a hierarchical model by a Poisson process. Results - a) the frequency of VPCs follows a circadian rhythm, closely related to the hourly variations of the mean heart rate; b) disregarding the heart rate influence on the variability of the ventricular arrhythmia, its behavior was at random and unpredictable; c) the minimal percentual reduction in VPCs/h that discriminated between antiarrhythmic effect and spontaneous between antiarrhythmic effect and spontaneous variability was 121.86% for sevenhour, 58.42% for 21-hour and 38.45% for 42-hour electrocardiographic monitoring periods; d) the same approch for the VCPCs revealed values of 133,8%, 63.21% and 41.3% respectively
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Chagas Cardiomyopathy/physiopathology , Sleep , Wakefulness , Circadian Rhythm , Electrocardiography , Cardiac Complexes, Premature/physiopathology , Cardiac Complexes, Premature/drug therapy , Analysis of Variance , Anti-Arrhythmia Agents/therapeutic use , Chronic Disease , Heart Rate , Chagas Cardiomyopathy/drug therapyABSTRACT
Este estudo clínico comparou a eficiência da remoçäo de placa bacteriana supragengival com taça, cone de borracha e uma mistura cremosa de pedra-pomes e água em motor de baixa velocidade, versus o sistema Profident com jato de bicarbonato de sódio, água e ar. Foram selecionados 100 pacientes com gengiva clinicamente saudável ou com gengivite leve. Em cada paciente foram feitos dois quadrantes para cada método. A eficiência dos dois métodos foi semelhante e a preferência dos pacientes foi para o sistema taça de borracha. O sistema Profident provocou mais queixa de dor, ou desconforto e sangramento gengival, sendo o método mais rápido