Calcification of basal ganglia in chronic hypoparathyroidism

Hypoparathyridism and pseudohypoparathyroidism are the common causes of pathological calcification in the brain. Though in 0.3- 1.5% cases it can be physiological, we describe a case of pathological basal ganglia calcification due to hypoparathyroidsm. A 39 years old diabetic lady who presented with neuropsychiatric problems and seizures and finally diagnosed as a primary hypoparathyroidism with symptoms related to metastatic calcification in the brain. This case emphasizes the importance of thinking about the whole spectrum of the disease even though the biochemical markers are stable on treatment