ABSTRACT
The purpose of this study is to evaluate histologically the role of Cerasorb bone graft substitute material [beta-tricalcium phosphate] as an augmentation method for filling bony defect adjacent to the dental implant, and to evaluate the state of bone osseointegration in comparison to Frios Algipore bone graft substitute material, currently used. Fifteen New Zealand white male rabbits of 4 - 6 months in age and of 2-2.5 Kg weight were used in the study. The animals were divided into three groups, each group consist of five animals with insertion of dental implant in the right femur with creation a traumatic bone defect 3x3 mm in diameter around the coronal part of dental implant The animals were left for healing without augmentation as for the control group and which augmented with Cerasorb and Algipore bone substitute for the other two groups. Animals were scarified at 2, 4, and 12 weeks postoperatively. The histological findings shows that Cerasorb bone substitute resulted in faster resorption and early initiation of the newly bone formation. The bone become completely matured during 12[th] weeks with successful bone osseointegration and direct contact to the implant surface, in comparison to the Algipore bone substitute material that show delayed resorption and longer time for new bone formation. There was an intervening layer between the bone and Algipore bone grafted material. The study concludes that the use of Cerasorb bone substitute material is more preferable as augmentation procedure for bony defect healing around implant site than the use of Algipore bone substitute material