ABSTRACT
Introduction: Cardiac dysfunction in patients with cirrhosisoccurs in the setting of a circulatory dysfunction characterizedby a marked splanchnic arterial vasodilation. Circulatory changescan lead to the cardiac dilatation of the left chambers and thedevelopment of functional changes in the heart. The present studyis intended to assess cardiac functions in patients of liver cirrhosis.Material and methods: It was a cross sectional study conductedamong 74 diagnosed cases of liver cirrhosis, admitted todepartment of general medicine, KIMS Hospital during the 6months study duration.Results: Overall LVDD was diagnosed in 59 cases (79.73%).Out of which, 47.29% cases presented with Stage 1 (impairedrelaxation) LVDD, Stage 2 LVDD (pseudo normal) among31.08% and only one patient had severe restrictive type of(Stage 3) LVDD.Conclusion: Left ventricular diastolic dysfunction iscommonly associated with advancement of hepaticdysfunction while systolic function is maintained till advancedhepatic failure
ABSTRACT
Introduction: Stroke is defined by (WHO) World HealthOrganization as ‘a clinical syndrome consisting of rapidlydeveloping clinical signs of focal (or global in case of coma)disturbance of cerebral function lasting more than 24 hour orleading to death with no apparent cause other than a vascularorigin.’ There are few studies conducted in Indian scenario,which shows the role of serum uric acid in cases of acuteischaemic stroke. So the present study aimed at evaluatingrole of uric acid in assessing severity of acute ischemic stroke.Material and methods: It was an Analytical, Noninterventional Prospective study conducted among 100 casesof acute ischaemic stroke admitted in medicine ward and ICUat Krishna hospital, Karad over the period of 18 months, whofulfilled inclusion criteria were included in our study.Results: In the present study, serum uric acid levels and itsdistribution was carried out. Mean levels of Serum Uric acidwas 4.92 ± 1.89 mg/dl. Maximum value being 8.4 mg/dl andminimum value was 1.2 mg/dl.Conclusion: The severity of acute ischaemic stroke wasproved to be directly proportional to the mean serum uric acidlevels in the present study.