ABSTRACT
Resumen Propósito: analizar los LIOs acrílicos hidrofóbicos AcryS of de nuestro banco de lentes explantados para establecer la presencia de microvacuolas(glistenings), determinar su frecuencia y definir si existe una correlación con los datos clínicos para cada uno.Materiales y Métodos: se realizó análisis clínico-patológico de todos los lentes hidrofóbicos AcrySof® (n=100) que hacen parte del banco de más de 5.000 explantes de nuestro laboratorio. Se efectuó evaluación microscópica y se determinó la presencia de las microvacuolas; adicionalmente se estimó la severidad de las mismas y se hizo una correlación con los datos clínicos para cada lente.Resultados: el análisis foto microscópico reveló la presencia de microvacuolas en 43 de los 100 LIOs evaluados: las microvacuolas fueron clasificadas como...
Purpose:To analyze the AcrySof hydrophobic intraocular lens from our database in order to establish the presence of the microvacuoles (glistenigs), determine its frequency, and define clinicopathological correlation in each case.Materials and Methods: A clinicopathological analysis was performed in all the explanted AcrySof IOLs (n=100) that were accessioned in ourlaboratory database of more than 5,000 explants. Applying photo microscopy, we estimated the number of glisteningscases, evaluated their severity, and correlated them with clinical findings.Results: The laboratory analysis revealed microvacules in 43 out of the 100 evaluated lenses. Of those cases, 14 were mild, 17 were moderate, and 12 were marked. Of the 43 lenses in which the vacuoles were identified, only 6 had been diagnosed clinically...
Subject(s)
Lenses, Intraocular , VacuolesABSTRACT
Posterior capsule opacification (PCO, secondary cataract, after cataract) is a nagging postsurgical complication following extracapsular cataract surgery (ECCE) and intraocular lens (IOL) implantation. PCO should be eliminated since it has deleterious sequelae and Neodynium: Yttrium Aluminium Garnet (Nd: YAG) laser treatment often is an unnecessary financial burden on the health care system. PCO following cataract surgery could be a major problem, since patient follow-up is difficult and the Nd:YAG laser is not always available. Advances in surgical techniques, IOL designs/biomaterials have been instrumental in bringing about a gradual and unnoticed decrease in the incidence of PCO. We strongly believe that the overall incidence of PCO and hence the incidence of Nd:YAG laser posterior capsulotomy is now rapidly decreasing - from 50% in the 1980s and early 1990s to less than 10% currently. Superior tools, surgical procedures, skills and appropriate IOL designs have all helped to significantly reduce this complication. In this article, we review the aetio pathogenesis, experimental and clinical studies and propose surgical and implant-related factors for PCO prevention. Careful application and utilisation of these factors by surgeons could lead to a significant reduction is secondary cataract, the second most common cause of visual loss worldwide.
Subject(s)
Animals , Cataract/etiology , Cataract Extraction , Humans , Laser Therapy , Lens Capsule, Crystalline/pathology , Lens Implantation, Intraocular , Postoperative Complications , Risk FactorsABSTRACT
Cataract surgery with intraocular lens (IOL) implantation has become the most common and most successful of all operations in medicine. Sir Harold Ridley's first cataract extraction with implantation of an IOL marked the beginning of a major change in the practice of ophthalmology. Millions of patients worldwide have benefited from Sir Ridley's invention, and are likely to continue to derive benefit from this device. However, the development of the IOL was not without its share of ups and downs. Sir Harold Ridley, the inventor of IOL, died at the age of 94, on 25 May 2001, and ophthalmology lost one of its greatest and most influential practitioners. We are happy that he lived to enjoy the fruits of his labour--to see the amazing improvements and the expansive growth that evolved in the cataract-IOL technique, from early and unsatisfactory operations in previous decades, to the superb results attainable today. The invention of the IOL has not been just the addition of one new form of treatment, but rather, Sir Harold's tiny disc-shaped sliver of plastic has changed the world so that our patients may better see it. This article presents a brief biographical sketch of Sir Harold and lists his major inventions and contributions to ophthalmology.
Subject(s)
Cataract Extraction/history , England , History, 20th Century , History, 21st Century , Humans , Lens Implantation, Intraocular/history , Lenses, Intraocular/history , Ophthalmology/historyABSTRACT
Objetivo: Relatar um caso mostrando os resultados da análise patológica de uma lente intra-ocular (LIO) acrílica hidrofílica com elevado conteúdo de água, explantada devido à impregnação por azul de tripano. Local: Serviço de Oftalmologia do Hospital Geral da Piedade, Rio de Janeiro, RJ, Brasil; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Métodos: Neste caso uma LIO AcquaTM (Mediphacos, Belo Horizonte, MG) foi explantada no quadragésimo dia de pós-operatório devido à impregnação de azul de tripano utilizado para corar a cápsula anterior durante a facoemulsificação. A LIO foi enviada para realização de análise macro e microscópica no estado seco e após hidratação. Resultados: A análise revelou que a impregnação em azul mais densa ocorreu no componente óptico da LIO, especialmente na periferia óptica. A impregnação em azul não pôde ser removida após 24 horas de imersão da LIO em solução salina balanceada a 37° C. Conclusão: A LIO AcquaTM é implantada no estado seco e sua hidratação/expansão depende dos fluidos que estão dentro do saco capsular. O uso de corantes capsulares deve ser evitado se esta LIO vai ser implantada.
Subject(s)
Humans , Male , Lens Implantation, Intraocular , Trypan Blue , Aged, 80 and over , Outcome and Process Assessment, Health Care , Postoperative ComplicationsABSTRACT
We report the clinicopathological findings of a human pseudophakic globe obtained postmortem, containing both anterior and posterior chamber intraocular lens, a condition we termed "bipseudophakia".