ABSTRACT
PURPOSE: To evaluate the effects of acupuncture (Ac) and electroacupuncture (EAc) on oxidative stress and inflammation in testis torsion/detorsion (T/D) model in rats. METHODS: Thirty male Wistar rats were randomized into five groups. G1 Group (Sham) served as control. The remaining groups were submitted to spermatic cord torsion (720°) for 3 hours, followed by detorsion and reperfusion for 4 hours. Before detorsion G3, G4 and G5 rats were treated with Ac, EAc 2Hz and EAc 10 Hz, respectively, applied to acupoint Gulai (S-29) bilaterally under anesthesia for 5 minutes. Next, the testes were detorsioned and reperfused for 4 hours. Afterwards, blood samples and the right testis were collected for biochemical assays: reduced Glutathione (GSH), Malonaldehyde (MDA), Myeloperoxidase (MPO). RESULTS: EAc stimulation (2 and 10 Hz) promoted significant increase in concentrations of GSH in plasma and testis of G4-G5 rats, compared with G1. There was significant increase of tissue MDA in groups G4-G5 and plasma MDA in all groups, compared with G1. There was a significant reduction in MPO activity in groups G4-G5 compared with G1. CONCLUSION: Electroacupuncture stimulation (2 and 10 Hz) attenuates oxidative stress and inflammatory response in rats subjected to testicular torsion/detorsion. .
Subject(s)
Animals , Male , Acupuncture Points , Electroacupuncture/methods , Oxidative Stress , Spermatic Cord Torsion/therapy , Glutathione/blood , Lipid Peroxidation , Malondialdehyde/blood , Peroxidase/blood , Random Allocation , Rats, Wistar , Reproducibility of Results , Reperfusion Injury/therapy , Spermatic Cord Torsion/metabolism , Time Factors , Treatment Outcome , Testis/blood supply , Testis/metabolismABSTRACT
Coccidioidomycosis is a systemic mycosis with a variable clinical presentation. Misdiagnosis of coccidioidomycosis as bacterial pneumopathy leads to inappropriate prescription of antibiotics and delayed diagnosis. This report describes an outbreak among armadillo hunters in northeastern Brazil in which an initial diagnosis of bacterial pneumonia was later confirmed as coccidioidomycosis caused by Coccidioides posadasii. Thus, this mycosis should be considered as an alternative diagnosis in patients reporting symptoms of pneumonia, even if these symptoms are only presented for a short period, who are from areas considered endemic for this disease.
Subject(s)
Adolescent , Animals , Humans , Male , Middle Aged , Armadillos/microbiology , Coccidioidomycosis/diagnosis , Lung Diseases, Fungal/diagnosis , Pneumonia, Bacterial/diagnosis , Pneumonia/diagnosis , Brazil/epidemiology , Coccidioides/isolation & purification , Coccidioidomycosis/epidemiology , Disease Outbreaks , Lung Diseases, Fungal/epidemiology , Pneumonia, Bacterial/drug therapy , Pneumonia/epidemiology , Soil MicrobiologyABSTRACT
Os autores relatam um caso de carcinoma papilifero oculto da tireoide com comprometimento linfatico extenso e a distancia, ressaltando a raridade desta apresentaçao. Tecem comentarios sobre a incidencia e prognostico do carcinoma papolifero oculto da tireoide. Finalizam fazendo uma breve revisao dos casos existentes na literatura medica
Subject(s)
Carcinoma, Papillary , Lymphatic Metastasis , Thyroid GlandABSTRACT
Apresentam um caso raro de rabdomiossarcoma primário do coraçäo diagnosticado pós-mortem. O paciente, de 33 anos, referia queixas de dispnéia de esforço e perda ponderal importante há seis meses, tendo desenvolvimento um quadro de insuficiência cardíaca congestiva refratária à terapêutica administrada, e evoluindo para tamponamento cardíaco e óbito, quatro dias após a admissäo. Os autores fazem uma revisäo dos achados clínicos e patológicos da entidade, mostrando aspectos que podem ser de utilidade na prática médica diária, para diagnóstico in vitam
Subject(s)
Adult , Male , Heart Neoplasms/pathology , Rhabdomyosarcoma/pathologyABSTRACT
Os autores relatam a ocorrencia de um caso de gravidez ovariana a termo com morte fetal recente, atendido na Maternidade-Escola Assis Chteaubriand (Fortaleza). A paciente apresentava sinais de toxemia e defesa abdominal, simulando esta ultima quadro ocasionado por rotura uterina.A autopsia fetal nao revelou malformacoes externas ou viscerais. Justificam a dificuldade do diagnostico precoce, enfatizando a raridade do fenomeno