Effect of yellow-tinted intraocular lens on standard automated perimetry and short wavelength automated perimetry in patients with glaucoma

To investigate the effect of cataract surgery and yellow-tinted intraocular lens [IOLs] implantation on perimetry indices of short-wavelength automated perimetry [SWAP] and standard automated perimetry [SAP] testing in patients with coexisting cataract and glaucoma. In this prospective comparative case series, phacoemulsification with implantation of yellow-tinted Acrysof Natural IOL was performed in 16 eyes of 16 patients with visually significant cataract [best-corrected visual acuity [VA] better than 20/120] and mild to moderate glaucoma. Pre- and postoperative values for VA and for perimetry indices including mean deviation [MD], pattern standard deviation [PSD], and foveal threshold [FT] from both SAP and SWAP testing were compared. Postoperative VA improved significantly after cataract surgery and yellow-tinted IOL implantation [P < 0.001]. After cataract extraction and IOL implantation, MD and FT on SWAP testing improved significantly [P = 0.001]; however, there was no statistically significant change with SAP testing between the pre- and postoperative perimetry indices. There was no statistically significant change in PSD with either SAP or SWAP testing postoperatively. The differences between pre- and postoperative values for all perimetry indices under study were not significant when comparing SAP with SWAP tests, except for MD which had improved statistically significantly in SWAP testing [P = 0.03]. In mild to moderate glaucoma patients with cataracts, the perimetry indices of SWAP testing improved after phacoemulsification and yellow-tinted IOL implantation. This suggests that the yellow-tinted IOLs have less effect on SWAP testing than visually significant cataracts

Topical mitomycin-C versus subconjunctival 5-Fluorouracil for management of bleb failure

To compare the efficacy and safety of topical mitomycin C [MMC] drops with that of subconjunctival 5-fluorouracil [5-FU] injections for management of early bleb failure after trabeculectomy or combined phacoemulsification and trabeculectomy with posterior chamber intraocular lens implantation [PT+PCIOL]. In a randomized comparative study, 37 eyes of 37 patients with impending early bleb failure received MMC 0.02% eye drops for 2 or 4 weeks [19 eyes] or subconjunctival 5-FU injections, 5 mg per dose [18 eyes]. Complete success was defined as 5 < IOP