ABSTRACT
This randomized clinical trial was aimed at comparing the outcomes of palatal connective tissue+ Bio-Oss + PRGF versuscollagen membrane + Bio-Oss+ PRGFin the treatment of intrabny defects. Fifteen patients affected by chronic periodontitis were enrolled. Each patient had at least two intrabonydefect [>/= 3mm]. They were randomly assigned into two groups: patients treated i] with collagen membrane+PRGF+Bio-oss [control group] and ii] with palatal connective tissue as membrane + PRGF+Bio-Oss [experimental group]. Clinical and intrasurgical examinations included probing depth[PD], clinical attachment level[CAL],gingival recession[GR],defect fill[DF], alveolar crest level[AC] and defect resolution[DR] were measured at baseline and after 6 months with re-entry surgery. Statistical analysis was performed usingTwo-way Repeated Measure ANOVA and Wilcoxon. After 6 months, all of the evaluated clinical parameters showed statistically significant changes from baseline within each group [p< 0/05]. The test group showed a significantly smaller amount of gingival recession as compared with control group.[0/8mm versus 1/7mm respectively; P<0/05] But there were not any statistically differences in other clinical parameters between the test and control groups[P>0/05]: pocket depth reduction [3/7mm versus 3/5mm], clinical attachment gain [1/8mm versus 1/6mm], alveolar crest loss [1/8mm versus 1/7mm], defect fill[2/3mm versus 2/2mm] and defect resolution [4/1mm versus3/9mm]. According to the results obtained from this study it can be suggested that clinical effects of application of palatal connective tissue as a membrane and collagen membrane, in combination with Bio-Oss and PRGF in treatment of vertical bone defects, did not have any statistical significant differences except for gingival recession that was statistically smaller in connective tissue group