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Rev. Soc. Bras. Med. Trop ; 50(2): 243-247, Mar.-Apr. 2017. tab, graf
Article in English | LILACS | ID: biblio-1041402

ABSTRACT

Abstract INTRODUCTION: We compared the prevalence and antimicrobial susceptibility of non-fermenting gram-negative bacilli (NFGNB) isolated from clinical samples at a Brazilian tertiary care hospital in 2008 and 2013. METHODS: Collected data included patient's name, age, sex, inpatient unit, laboratory record number, type of biological material, culture test result, and antimicrobial susceptibility of isolated strains. RESULTS: Out of 19,112 culture tests analyzed, 926 (4.8%) were positive for NFGNB. Among these, 45.2% were metallo-beta-lactamase (MBL) producing strains. CONCLUSION: Between 2008 and 2013, the number of MBL-producing NFGNB isolates increased by 21.5%, which was accompanied by a consequent reduction in susceptibility to antimicrobials.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Young Adult , Gram-Negative Bacterial Infections/microbiology , Gram-Negative Bacteria/drug effects , Anti-Bacterial Agents/pharmacology , beta-Lactamases/biosynthesis , Microbial Sensitivity Tests , Prevalence , Tertiary Care Centers , Gram-Negative Bacteria/isolation & purification , Gram-Negative Bacteria/enzymology , Middle Aged
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