ABSTRACT
Introduction: Relative afferent pupillary defect (RAPD) is an imperative sign to assess the retinal and optic nerve function. However, RAPD is subjective, so leads to discrepancies and hence there is the need for a precise quantification of the same. Materials and Methods: 80 subjects were enrolled in the study, pupillary reactions were measured using RAPDx Expanded Pupil Diagnostics (Konan Medical USA, Inc., Irvine, CA, USA) and were compared with neutral density filter (NDF) (Gulden Ophthalmics) and swinging flashlight test. Results: The mean pupillary reactions assessed on NDF was less than 0.3 log units and that assessed on RAPDx was 0.28 log units (P<0.001 spearman’s coefficient). Conclusion: RAPDx is comparable to NDF and may be used as a screening tool in Ophthalmology clinic, and gives an accurate and precise quantification of pupillary responses.