ABSTRACT
Objective: the aim of this study is to evaluate pancytopenia and to know frequency of diseases presenting as pancytopenia
Methods: this is a retrospective study. Seventy six patients irrespective of age and sex were included in this study from August 2008 to June 2011. Patients on chemotherapy and radiotherapy were excluded from study. Blood counts on hematology analyzer, peripheral smear examination, bone marrow aspiration and trephine biopsies of all patients were performed according to standard protocols
Results: diseases leading to pancytopenia in this study in descending order of frequency were aplastic anemia 29[38%], hypersplenism 20[26.3%]. megaloblastic anemia 15[19.7%],myelodysplastic syndrome[MDS] 10[13 .15% ], acute leukemia 1 [1.3%] and granuloma formation in bone marrow 1 [1.3%]
Conclusions: aplastic anemia, hypersplenism and megaloblastic anemia were common causes of pancytopenia in this study