ABSTRACT
Acute kidney injury is a threatening complication of pregnancy causing serious maternal and fetal morbidity and mortality,common in developing countries.METHODS:A observational study was done between January 2018 to November 2018 to report the incidence,clinical spectrum and maternal&fetal outcome in AKI.RESULTS:Total number of patients 40,Mean age–25.3± 4.3 yrs.The incidence of AKI in pregnancy was 6%.Incidence of AKI most common in Postpartum period(80%),causes of AKI was Sepsis(40%),HELLP(20%),Postpartum hemorrhage (20%),Auptio placenta (15%),Acute fatty liver of pregnancy (5%).Among them 80% of patients having preeclampsia as common risk factor.Live births was 80%.Among total pregnancy related AKIs 14 patients were managed conservatively and 26 needed dialysis. recovered patients were (N=38) 95%,and mortality was (N=2)5%.CONCLUSION:AKI in pregnancy commonly occurred in Postpartum period and Sepsis is the most common etiology
ABSTRACT
Paraquat poisoning is one of the causes of AKI, the mechanism of toxicity being the production of reactive oxygen species,thereby causing toxicity at the cellular level. The aim of this study is to determine the requirement of haemodialysis and the severity of toxicity, depending upon the amount ingested.It is found that in Paraquat poisoning, the intervention with pre–emptive haemodialysisis not useful in decreasing the mortality. Ingestion under the influence of alcohol has higher mortality.Amount of poison ingested has a great impact and is directly proportional to the mortality. Oral ulcers, hepatic involvement, ARDS and MODS all reflected grave prognosis ultimately leading to death. The overall mortality in the study is 51%.