ABSTRACT
Since January 2000 till 2004 we performed nephrectomy on 33 patients having large renal tumors [more than 8cm] at Damanhour Oncology Center. We excluded patients who had lung metastasis or adherence to nearby organs. Thirty of the tumors were found to be malignant and only 3 were benign. The tumor was slightly more common in females [17 patients] than in males [16 patients]; also it was affecting the right kidney in 48.5% and the left kidney in 51.5% of the patients. Out of 30 patients having malignant tumors 7 patients died and 23 patients survived till June 2005. The mean follow-up period was 31.95 month +/- 4.97. The microscopic picture of the renal tumors of the surviving patients was clear cell type [23 patients 76.6%]. Meanwhile four of the patients who had died also had clear cell type renal cell carcinoma, and the other three had collecting duct carcinoma. We found that lymph node involvement was significantly positive in the patients who had died. Neither the capsular infiltration nor the tumor size was significantly different between the patients who had survived and the patients who had died. Lymph node involvement was significantly positive in the patients who died [86%]. Neither the capsular infiltration nor the tumor size was significantly different bet%veen the surviving patients and the patients who had died. Among large renal tumors benign tumors could be found [9%]