Neutral lipid storage disease-a case report

Neutral lipid storage disease is a rare autosomal recessive disorder characterized by non-bullous ichthyosiform erythroderma, liver steatosis, hepatosplenomegaly, cataracts, ataxia, bilateral sensorineural hearing loss, skeletal and cardiomyopathy, growth and mental retardation. We report a case of neutral lipid storage disease in a 14 months old child

EEG findings in post stroke seizures: an observational study

Stroke is an important cause of epilepsy especially in the elderly. We conducted an observational study in a tertiary referral center to describe different EEG findings in patients who developed seizures after stroke. We reviewed alt EEGs that were performed for evaluation of seizures after stroke from January to December 2006 and retrospectively recorded demographic data, side of stroke, type of seizures and EEC findings. All this information was entered on a specially designed proforma. A total of 41 patients with post stroke seizures had EEG done at our laboratory that were reviewed and analyzed. Of these patients, 51.2% [n=21] were males [mean age 60.7; range 22-84 years] and 48.8% [n=20] were females [mean age 63; range 3-90 years]. The commonest seizure semiology was generalized seizure in 56.1% [n=23], focal seizures in 36.6% [n=1 5] and focal with secondary generalization in 7.3% [n=3] patients.51 .2% [n=21] had right hemispheric involvement, 26.8% [n=11] had left hemispheric involvement and in 22% [n=9] patients side of stroke was not identified. The commonest EEG finding was generalized slow waves seen in 39.0% [n=16] patients. Other abnormalities found were focal slowing in 19.5% [n=8], focal sharp and stow waves in 9.8% [n=4], focal spikes and slow waves in 4.9% [n=2], focal sharp waves in 4.9% [n=2] of the patients. Focal spike waves in 2.4% [n=1] and PLEDS were seen in 2.4% [n=1] patients. 17.1% [n=7] patients had normal EEG. Generalized seizures and generalized slowing on EEG were the commonest findings in our patients who developed seizures after stroke. The commonest epileptiform discharges were focal sharp and slow waves seen in 9.8% of patients with post stroke seizures