ABSTRACT
To study the effects of electromagnetic radiations on follicles of Thyroid gland of mice, Laboratory based randomized controlled trials. The study was carried out in department of Anatomy. Army Medical College Rawalpindi in collaboration with National Institute of Health, Islamabad from November 2009 to November 2010. Twenty adult Balb/C male mice were divided randomly into two study groups, comprising of 10 animals in each group. Group A was kept under experimental conditions without mobile phone exposure, group B exposed to radiations for 1 hour /day, for two months from mobile phone set. Thyroid glands were removed and sectioned after exposure period. Sections were stained with hematoxylin and eosin for microscopic examination. Results showed statistically significant difference in number and mean size of Thyroid follicles in gland of experimental groups. Thus it is concluded that exposure to EMFs causes decrease in size and increase in number of follicles of thyroid gland of mice, indicating hyperactivity of gland
ABSTRACT
Research conducted over PCOS by various groups in the world indicated the effect of Metformin on PCOS. Previous studies suggest that Glucophage by reducing hyper-insulinemia is clinically useful in the treatment of polycystic ovary syndrome [PCOS]. Our Objective was to observe the role of Glucophage in treating infertility of polycystic patients within three months in Group A and six months in Group B patients. Another aim was to assess the decrease in hyper-insulinemia and Leptin levels by Glucophage in our population. This study was carried out at the Department of Obstetrics and Gynaecology, Pakistan Institute of Medical Sciences, and Noor Specialised Clinic Islamabad, from Oct 2004 to Apr 2008. One hundred and seventy women in Group A and 145 in Group B fulfilling the clinical and biochemical criteria for PCOS were enrolled. Glucophage was started at an oral dose of 500 mg/day and maintained at 1500 mg for 3 months or 6 months in both Groups. Besides ultrasonography, serum FSH, LH, fasting insulin, fasting blood sugar, glucose insulin ratio, Quantitative Insulin Sensitivity Check Index [QUICKI] and leptin levels were performed. After three months in Group A and six months in Group B these criteria were again assessed. After 3 and 6 months of Metformin therapy, significant reduction in biochemical parameters was observed such as fasting glucose, insulin and leptin. Data were analysed using SPSS by paired t-test and ANOVA. Six months treatment with Glucophage proved to be better option for infertile PCOS
ABSTRACT
Dengue is an important vector borne viral disease of public health significance. Dengue fever is on the rise in Pakistan with considerable morbidity and mortality in recent outbreaks. We undertook the study to analyze the prevalence of Dengue fever in Rawalpindi and Islamabad region. The object of our study was to estimate the burden fever in Rawalpindi and Islamabad region. Another aim of our study was to evaluate and if possible alleviate the anxiety associated with dengue fever. We wanted to find out the factual prevalence of the disease. We aimed to determine the most common age group and gender of the illness as well. Cross Sectional Study. This study was conducted in Benzair Bhutto Hospital [BBH] and Pakistan Institute of Medical Sciences [PIMS] in Rawalpindi and Islamabad from 1[st] September to 15[th] November 2011. People of all ages and both sexes with suspicion of Dengue were included in the study. A total of 16616 people turning up at these hospitals were tested for dengue virus. Only 2269 were positive for disease [13.6%]. Male to female ratio came out to be 2.1:1 and maximum number of cases belonged to age group 21-30 years. The number of cases turning up with Dengue suspicion is out of proportion to actual disease burden. Thus we need to alleviate the anxiety associated with the disease. There is a genuine need for strict adherence to preventive control measures and research needs to be undertaken in order to reduce the mortality and morbidity associated with the Dengue
Subject(s)
Humans , Female , Male , Anxiety/therapy , Age Groups , Cross-Sectional Studies , PrevalenceABSTRACT
Broad ligament haematoma is a rare complication of a normal vaginal delivery. We report a 24 year old patient who developed this complication and was managed successfully