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Alexandria Journal of Pediatrics. 2015; 29 (1): 46-49
in English | IMEMR | ID: emr-181845

ABSTRACT

Objective: To study Bone density and serum osteocalcin level in children with acute lymphoblastic leukemia


Methods: Serurn osteocalcin and DXA scan were evaluated in 45 children with ALL, 15 at diagnosis and before starting chemotherapy, 15 during chemotherapy and 15 after completing their treatment regimen


Results: From the total 45 patients, 23 [51.1%] had low osteocalcin level and 36 [80%] had low bone rnineral density [48% had osteopenia and 32% had osreoporosis]


Conclusion: Musculoskeletal abnormalities are present in children with ALL at diagnosis, during treatment] and persist as long-term squeal after treatment

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