ABSTRACT
Background: Acute lung injury [ALI] is an example of a critical care syndrome with few therapeutic modalities once the syndrome is fully established, and little has been done on the prevention of ALI
Aim of the work: The aim of this work was to early identify the onset of acute lung injury [ALI] on admission and to prospectively evaluate the lung injury prediction score [LIPS]
Patients and methods: The study was carried out on 100 patients who aged >18 years, patients who had one or more of the acute lung injury [ALI] predisposing conditions on admission or within 6 h after were subjected to lung injury prediction score [LIPS]
Results: Acute lung injury developed in 15 patients, 11 patients [73.3%] had LIPS >3, while 4 patients [26.7%] had LIPS 3, with a statistically significant relationship between patients above and below LIPS value of 3 [P = 0.000], LIPS cutoff value of >/=3.5 on admission had a 73% sensitivity and 95% specificity with an area under the receiver operating curve of 0.883 [95% CI 0.782 to 0.984]. Sepsis and pneumonia were the most frequent risk factors [60%]
Conclusions: Lung injury predictive score [LIPS] could early predict patients at risk to develop ALI on admission, Hyperbilirubinemia, high blood urea level and abnormal chest X-ray on admission were not included in the original LIPS but had significant association with development of ALI