ABSTRACT
Background: COVID-19 pandemic is a public health emergency of international concern that can result in severe mental health conditions like depression and fear in health-care professionals (HCPs). Methods: A cross-sectional study was conducted, where 834 HCPs were self-recruited via social media. Multiple linear regression analyses were performed to identify predicting factors. Results: Approximately one-third of the total participants were depressed (27.3%) and those with depressive symptoms had significant fear of COVID-19. Significant risk factors for depressive symptoms were being female, being married, having no children, having high risk elderly persons at home, being afraid of death due to COVID-19 and having comorbid diseases. Fear of death due to COVID-19 was the most common significant contributing factor the scales for depression model, ?=0.397, for fear of COVID-19 model and ?=0.478 respectively. Quality of PPE played a vital role for depression as majority of HCPs. About 65.3% of HCPs who were restless while examining a patient with flu symptoms and majority of HCPs who felt insecure about their family members. Conclusions: Most of the HCPs faced several challenges during COVID-19 and psychological impacts of frontline HCPs were associated with interventions and rehabilitations to improve the mental health.
ABSTRACT
O uso racional de medicamentos é indispensável para garantir a qualidade e eficácia de um tratamento medicamentoso. Diante disto, a utilização de medicamentos durante a gestação deve ser analisada e acompanhada minuciosamente para minimizar os riscos e possíveis conseqüências ao feto e à gestante. Foram analisadas 100 receitas medicamentosas para gestantes, internadas no Hospital e Maternidade Mãe do Divino Amor na Providência de Deus do município de Mirassol, SP, utilizando os indicadores de prescrição propostos pela OMS, análise de interação medicamentosa por programas informatizados e pela literatura, classificação dos medicamentos encontrados segundo a classificação da segurança do fármaco durante a gravidez prescrita pelo Food and Drug Administration (FDA) a Relação Nacional de Medicamentos Essenciais (RENAME) e a Classificação Anatomical Therapeutic Chemical (ATC). Na análise dos indicadores de prescrição, nas 100 receitas avaliadas, encontrou-se a média de 2,6 medicamentos por prescrição; 21,5% de medicamentos prescritos pelo nome genérico; 40% delas contendo antibiótico; 59,4% com pelo menos um medicamento injetável e 58 % de medicamentos prescritos, presentes na Lista de Medicamentos Padronizados. Quanto à análise de interações medicamentosas, observa-se a prescrição do antibiótico cefalexina com o antiinflamatório cetoprofeno. Portanto, considerando-se os resultados obtidos no estudo e na revisão da literatura, sugere-se que as prescrições de medicamentos neste hospital para gestantes sejam melhor avaliadas segundo risco benefício, visando à minimização dos efeitos adversos desnecessários, tanto maternos como fetais.
The racional usage of medicines is indispensable to warrant the quality and efficacy of a medical treatment. Considering this, the use of remedies during pregnancy must be examined and followed in details to minimize the risks to the fetus and to the pregnant. A hundred of prescriptions to pregnant women interned at the Hospital Mãe do Divino Amor na Providência de Deus, in Mirassol city, São Paulo State, were analysed and compared with the prescription index designated by the WHO (World Health Organization). This work shows too the analysis of medicines interaction by softwares and literature and the classification of remedies by FDA (Food and Drug Administration) risk to the fetus, Rename (National List of Essential Medicines) and ATC (Anatomical Therapeutic Chemical). In one hundred of prescriptions analysed, there is a average of 2,6 medicines per precept, 21,5% of remedies prescribed by the generic name, 40% of indications of antibiotics, 59,4% of instructions with at least one medicine ministered by injection and 58 % of substances quoted in Remune (Municipal List of Essential Medicines). There was find only one interaction between the medicines: an antibiotic that belongs to the group of celafosporin and non-steroidal antiinflamatory. Thus, considering the results of the study and literature review, is suggested that the prescription of drugs in this hospital to betaken by the pregnantes be better assessed for risks and benefits, to minimize unnecessaru harm to the mother and the fetus.