Precocious puberty.

Sixty-five patients who presented with clinical features of precocious puberty during 1987-1993 at pediatric endocrinology unit, Siriraj ?Hospital, were studied. Female to male ratio was 6:1. Idiopathic true precocious puberty was the most frequent diagnosis in girls (56%) but 40 percent in boys had CNS lesions. Discriminant analysis showed that the difference between none age and chronological age (BA-CA) and height standard deviation score (htSDS) could discriminate between premature thelarche and precocious puberty with 92 percent accuracy, but not serum baseline FSH, LH and estradiol. Twenty seven percent of premature thelarche had remission in two years. Seventy eight percent of congenital adrenal hyperplasia were salt-losing type.