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1.
Mem. Inst. Oswaldo Cruz ; 97(8): 1079-1083, Dec. 15, 2002. tab, graf
Article in English | LILACS | ID: lil-326332

ABSTRACT

Sixty-five patients were diagnosed with visceral leishmaniasis (VL) on Margarita Island in the decade from 1990 to1999; 86.2 percent were <= 3 years old. All were leishmanin-negative at diagnosis. Evaluation of 23 cured patients in 1999 revealed that 22/23 had converted to leishmanin-positive; five had persisting antibodies to rK39 antigen, with no clinical evidence of disease. Leishmanin tests were positive in 20.2 percent of 1,643 healthy individuals from 417 households in endemic areas. Of the positive reactors, 39.8 percent were identified in 35 (8.4 percent) of the households, 15 of which had an antecedent case of VL, a serologically positive dog or both. Weak serological activity to rK39 antigen was detected in 3 of 488 human sera from the endemic areas. The presence of micro-foci of intense peri-urban transmission and the apparent absence of other Trypanosomatidae causing human disease offer a unique opportunity for the study of reservoirs, alternative vectors and evaluation of control measures on the Island


Subject(s)
Animals , Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Dogs , Antibodies, Protozoan , Leishmania donovani , Leishmaniasis, Visceral , Protozoan Proteins , Age Distribution , Analysis of Variance , Dog Diseases , Endemic Diseases , Enzyme-Linked Immunosorbent Assay , Incidence , Leishmaniasis, Visceral , Sex Distribution , Skin Tests , Statistics, Nonparametric , Venezuela
2.
Rev. cuba. oftalmol ; 5(2): 91-9, jul.-dic. 1992. tab
Article in Spanish | LILACS | ID: lil-120855

ABSTRACT

Se realiza un estudio prospectivo a 400 pacientes que presentaron mala visión de cerca y no tuvieron ninguna enfermedad asociada a su defecto visual. Entre las principales conclusiones figuraron que la presbicia predominó en los pacientes del grupo etáreo de 41 a 45 años, del sexo femenino, de procedencia urbana y cuya ocupación se relacionaba con la visión de cerca, y que apareciò en los amétropes alrededor de los 40 años y en los emétropes después de los 42. Los valores calculados para la corrección de la presbicia coincidieron en la mayoría de los pacientes con los referidos en las tablas. Los errores encontrados con más frecuencia al realizar la refracción fueron: la hipocorrección del defecto de lejos, que obligó a la utilización de adiciones superiores a las referidas en las tablas en algunos pacientes, y la hipecorrección del defecto de cerca, que ocasionó falsos diagnósticos de presbicia en menores de 40 años con insuficiencia de la acomodación


Subject(s)
Adult , Middle Aged , Humans , Female , Presbyopia/therapy , Prospective Studies
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