ABSTRACT
Maxillary canines are considered as the cornerstone of the mouth. This study aims to estimate the prevalence and unfold various patterns present in maxillary canine impactions using cone beam computed tomography [CBCT].Digital records of 3469 patient were collected from two different radiological units. Sorting of CBCT data was done for identification of maxillary impacted canine's cases. Data were analyzed statistically, and descriptive statics were generated for age, gender, quadrant, and position of impacted canines. Chi-square test was used to check the difference in the distribution of impacted canines regarding gender, quadrant and position of impacted teeth. A p-value of <0.05 was taken as significant.One hundred and eighty-seven patients were identified with impacted maxillary canines making a prevalence of 5%, with a mean age of 17.9 +2.65 years. 117 impacted canine cases were located in females while 70 impacted canine cases were in males. Female to male ratio was1.67:1. Statistically, a significant difference was noted between genders [p-value =0.00]. No difference was noted between genders regarding quadrant and position of impacted canines.Higher prevalence of impacted canine was noted in females, while left side predominance was found in both genders. Palatal impactions were most common while a higher prevalence of buccal impaction, than previously reported was noted in the present study
ABSTRACT
This study investigated the psychosocial risk factors of myocardial infarction and time related adverse effects of administration of streptokinase on short-term morbidity and mortality in patients with ST-segment-elevation myocardial infarction [STEMI]. One hundred patients with STEMI treated with streptokinase in the hospital setting were prospectively enrolled in the study. The primary outcome parameter was the incidence of major adverse cardiac events. During hospital stay the psychosocial and demographic risk factors were also investigated. The overall mortality rate was similar in both groups and it was not significant. [5.7% vs 14.5%; P = 0.18]. The number of recurrent chest pain was significantly higher in the group 2 compared to the group 1 [25% vs 62.5%; P = .01]. The number of hypotesion was significantly higher in the group 1 as compared to the group 2 [30.7% vs 6.2%; P = .009]. The demographic and psychosocial risk factors were recorded. The early intravenous administration of streptokinase in the hospital setting leads to a reduced rate of major cardiovascular events compared to delayed administration beyond 2 hours. However, mortality rates were not significantly affected. Secondary prevention should be targeted on modifiable demographic, dietary, and psychosocial risk factors of STEMI
ABSTRACT
<p><b>OBJECTIVE</b>To explore the efficacy of ethanolic leaf extract of Typhonium trilobatum L. Schott in treating diarrhea, pain and inflammation using experimental models.</p><p><b>METHODS</b>In the present study, acetic acid-induced writhing, xylene-induced ear edema and castor oil-induced diarrheal model were used to evaluate the analgesic, anti-inflammatory and anti-diarrheal activities, respectively. Acute toxicity test was carried out to fix the safe doses of the plant extract.</p><p><b>RESULTS</b>The plant extract demonstrated a significant inhibition of writhing (P<0.01) compared with the control group in acetic acid-induced writhing test in mice. The extract also significantly inhibited the xylene induced ear edema formation (P<0.05). In anti-diarrheal test, the extract significantly decreased the frequency of defecation and increased the mean latent period (P<0.01) in castor oil-induced diarrheal model mice at the doses of 250 and 500 mg/kg body weight.</p><p><b>CONCLUSIONS</b>These results suggest that the extract possesses significant analgesic, anti-inflammatory and anti-diarrheal activities that support to the ethnopharmacological uses of this plant.</p>