ABSTRACT
Background: Serum Ferritin is an acute phase protein and it is a marker of iron stores in the body. The HbA1c fraction is abnormally elevated in chronic hyperglycemic diabetic patients
Objective: To determine the association between serum ferritin and long term glycemic control by HbAIc in patients with diabetes mellitus type 2
Methodology: This was a case control study which was carried out in the chemical pathology department of Sheikh Zayed Medical College/Hospital, Rahim Yar Khan, from 1[ST] July 2016 to 31[ST] January 2017. A total of 290 study subjects were included in this study. 110[38%] were the cases [diabetics with high HbA1c]. Ferritin, hemoglobin, HbA1c, and fasting blood sugar were measured in blood samples. Exclusion criteria included anemia, or any other disease or drug that could affect ferritin levels. Results were analyzed statistically by t-test and Pearson correlation test. The data was entered and analyzed by SPSS version 17
Results: A total of 290 study subjects were included in this study.110 were the cases [diabetics with high HbA1c], and 180 normal subjects were included. The mean serum ferritin among cases was significantly higher than control group [137+/-64 vs. 94+/-61ng/ml]. [P<0.00]