ABSTRACT
Objective: To establish the hormonal, metabolic and clinical profile for Saudi women with polycystic ovary syndrome [PCOS]
Design: This is a prospective, cross-sectional study conducted at the University Hospital. All women were seen at the gynecology clinic. One hundred women aged between 18 and 45 years were included in the study; 50 women with polycystic ovary disease [PCOS] comprised the study group and 50 women without PCOS comprised the control group. The hormonal, metabolic and clinical profiles were assessed for both groups
Results: There are significantly higher levels of luteinizing hormone, prolactin, free testosterone dehydroepianosterone sulfate, 17 alpha-hydroxy progesterone and fasting insulin in the study group. There were no differences in the levels of total testosterone, estradiol and cortisone levels between both groups. The levels of follicular stimulating hormone and sex hormone binding globulin were significantly lower in the study group. There were no differences in the blood sugar level, cholesterol, triglycerides and low- and high-density lipoproteins. The womens' ages, body mass index, blood pressure, uterine dimensions and endometrial thickness were similar in both groups. The size of both ovaries was significantly greater in the study group. There were more follicles in the ovaries of the study group
Conclusion: Hormonal profile of Saudi women with PCOS was similar with what is already published in the medical literature. But, despite the fact that Saudi women with and without PCOS are overweight, they do not suffer from raised blood pressure and metabolic syndrome; this may be due to the fact that women included in this study were relatively young and the sample size might be too small to draw effective conclusions
ABSTRACT
Although appendiceal endometriosis is rare, appendix is the second most common site of intestinal endometriosis. Clinical diagnosis is difficult and histopathology is the only way to establish the diagnosis. We present a case of chronic pelvic pain secondary to appendiceal endometriosis and a review of the literature. There are no pathognomonic criteria to establish an accurate preoperative diagnosis. There is no specific radiologic test for diagnose. Laparoscopy provides detailed evaluation of the appendix but gross inspection of appendix alone is not enough to rule out the problem. The appendix may harbor endometriosis and could be a cause of chronic pelvic pain. When performing surgeries in a patient with chronic pelvic pain, surgeons should be aware of the possible contribution of the problem pelvic pain in patients with endometriosis. The appendix should be examined thoroughly during endometriosis-related operations. Appendectomy should be performed if the appendix looks abnormal