ABSTRACT
PURPOSE: To compare the predictive accuracy for future ischemic events of heart rate limited treadmill exercise test (HET) and coronary angiography (CA) applied to survivors of an uncomplicated myocardial infarction. METHODS: 142 consecutive patients (55 +/- 11 years, 80males), presenting a non complicated acute myocardial infarction (AMI) were included. HET was performed 10 +/- 3 days after AMI, and CA during hospital stay or within 4-6 weeks. HET positivity criteria were: 1) horizontal or down-sloping ST segment displacement > or = 1 mm; 2) angina; 3) arterial pressure drop during exercise; 4) low workload (< 6 METS); 5) complex ventricular arrhythmia. At CA lesions causing > or = 50of luminal reduction were considered significant. HET and CA results were correlated to ischemic events occurring during the follow-up (unstable angina in 20, cardiac death 6, and reinfarction 6). RESULTS: HET was positive in 69 (49) patients, exhibiting a positive predictive value for ischemic events (PV+) of 26and a negative predictive value (PV-) of 77. The mean event-free time was 43 +/- 3 months for positive HET and 46 +/- 3 months for a negative one (p = 0.48). CA showed 0-1 vessel involvement in 93 (66) patients and > or = 2 vessels in 49 (34) patients. The presence of multivascular disease at CA presented a PV+ of 37and PV- of 82; the mean event-free time was 37 +/- 4 months for patients with multivascular involvement and 48 +/- 2 months for patients without this pattern (p = 0.007). CONCLUSION: The predictive accuracy of HET for future ischemic events in the thrombolytic era is markedly reduced. This population of AMI survivors presents an overall good prognosis that seems to justify the poor predictive accuracy of this test.
Subject(s)
Humans , Adult , Middle Aged , Streptokinase , Myocardial Infarction/drug therapy , Thrombolytic Therapy , Aged, 80 and over , Predictive Value of Tests , Risk Factors , Follow-Up Studies , Survivors , Coronary Angiography , Chi-Square Distribution , Myocardial Infarction/diagnosis , Prognosis , Disease-Free Survival , Exercise TestABSTRACT
Objetivo - Mostrar a experiência do Serviço com a técnica de angioplastia coronária em pacientes com revascularização cirurgica prévia. Métodos - De janeiro de 1989 a janeiro de 1991, efetuaram-se 629 angioplastias coronárias (D) em 572 pacientes. Desses, 48 haviam sido previamente revascularizados entre 4 dias a 10 anos. Os locais de dilatação foram agrupados em: A) na circulação nativa não abordada cirurgicamente (26 pacientes); B) no segmento arterial proximal (4 pacientes) e distal (2 pacientes) a anastomose coronária; C) no enxerto venoso (16 pacientes). Resultados - Em 48 pacientes foram realizados 52 procedimentos de dilatação (A-30, B-6, C16) com sucesso primário global de 78%. Nos grupos B e C somados, 16 dilatações foram bem sucedidas (72%) e os 6 insucessos, todos do grupo C, foram devidos à instabilidade do cateter guia, impossibilitando atingir (4 casos) ou ultrapassar (2 casos) a lesão com o balão. Houve 1 óbito no grupo A e outro no grupo C. Conclusão - A angioplastia coronária é uma alternativa efetiva no tratamento da isquemia recorrente de pacientes previamente operados e os resultados são semelhantes aos da população geral de angioplastias.
Purpose - To show the author's experience with percutaneous transluminal coronary angioplasty (PTCA) in patients with prior coronary bypass surgery. Methods - Between January 1989 and January 1991, 629 PTCA in 572 patients were performed. Forty-eight had previous revascularization surgery with interval range of 4 days to 10 years. The PTCA sites were divided in three groups: A) native arterial segments, not affected by surgery (26 patients); B) native arterial segments proximal (4 patients) and distal (2 patients) to graft anastomosis; C) in the coronary vein graft (16 patients). Results - The overall primary success was 78%. In groups B and C, 16 procedures were successfully dilated (72%). All fuilares in group C were due to unstable problems in reaching (4 patients) or crossing (2 patients) the stenosis with the baloon. There was one death in group A and another in group C. Conclusion - Angioplasty is an effective alternative for treatment of recurrent ischemia in patients with prior myocardial revascularization surgery and in early results are comparable to the general angioplasty population.