ABSTRACT
The disruption of transaminases and phosphatases from the normal values denotes biochemical impairment and lesions and cellular function because involved in the detoxification metabolism and biosynthesis of macromolecules for different function. The results of the present study revealed that feeding chicken in profenofos contaminated feed at levels of 50, 100 and 200 ppm for three weeks, resulted in a significant of tissue they are energetic essential increase in the values of glutamic oxaloacetic transaminase [GOT], glutamic oxaloacetic transaminase [GOT], Alkaline phosphatase [A.P.] and cholesterol, especially at levels of 100 and 200 ppm. Upon return of normal feed free from profenofos for 10 days, these values decreased gradually but not to normal and the decreases were not significant