Study of Serum Albumin Level in Subjects with HIV Infection, in Relation to CD 4 Count, as a Marker of Immune Suppression

Introduction: HIV/AIDS Infection is one of the commonlyencountered illness in our setup. It causes morbidity andmortality worldwide, and the number of HIV-infected patientshas increased dramatically in the past decade. Current studyaimed to record serum albumin level in patients suffering fromHIV infection.Material and methods: A total of 175 subjects were studiedover a period of 3 months. History and examination weredone according to the proforma after taking written informedconsent. Routine investigations included CD 4 Count andLFT. All data were entered in the master chart and analysedusing SPSS Version 20 softwareResults: Out of 175 subjects majority were in age group of 41to 50 years (30.4%) with mean age around 42 years and 101subjects were males (57.7%). Low serum albumin was foundin 67.2% of subjects. 12% of the subjects had CD 4 Count ofless than 100 and among subjects with CD 4 Count of lessthan 100, 76% of the subjects had low serum albumin whichwas statistically significant with p value of 0.003.Conclusion: From the study can conclude that in HIV /AIDSpatients serum albumin levels correlate with CD 4 counts andcan be used as a marker of immune suppression.

Assessment of compliance with iron-folic acid therapy during pregnancy among postnatal mothers in a tertiary care centre, Mysuru

Background: Anemia is a condition where the red blood cells and their capacity to carry oxygen is not adequate to meet the physiological needs. In pregnancy iron demand is high and loss of appetite can adversely affect this condition. So, guidelines to combat anemia has provisions to provide iron in the form of iron folic acid tablets to pregnant women during antenatal and postnatal care. But compliance is still low among pregnant women who needs attention.Methods: This study included 192 postnatal mothers in Cheluvamba hospital, Mysore. Details about socio-demographic factors and number of tablets taken during antenatal period were collected using proforma. Pregnant women who had taken less than hundred tablets during antenatal period were considered non-compliant.Results: The overall compliance to iron folic tablets was 71%. The factors which were independently associated with non-compliance are nuclear family, less number of antenatal visit, tablets from private source, and anemia in current pregnancy. The reasons for non-compliance among the pregnant women who were non-compliant were inadequate counselling by health care worker followed by side effects, cost of tablets, ignorance and fear of side effects.Conclusions: Family support, adequate counselling and continuous supply of tablets free of cost would increase the compliance to tablets among pregnant women.