ABSTRACT
Background: Cellular glycosylation changes are associatedwith different types of neoplastic transformation. Fucose is adeoxyhexose sugar that the body requires for optimal functionsof cell to cell communications and which plays a role in severalbiological events. Fucose has been considered to play asignificant role in cancer and its spread. Alpha L Fucosidase(ALF) is an exoglycosidase involved in the hydrolyticdegradation of fucose containing components of glycoproteins,glycolipids and oligosaccharides. The significance of thisenzyme in human catabolism is implied by geneticneurovisceral storage disease. Altered levels of ALF has beenreported in the plasma/serum of patients with oral cancer.Aims: To investigate the clinical usefulness of serum fucoseand α-L-fucosidase in diagnosing oral pre-cancer and cancerand study the variations of the levels of both metabolites innormal, precancerous and cancerous conditions (Squamouscell carcinoma).Methodology: The study group comprised of 87 samples of(age range: 20-70 years): control samples – healthy individualswithout any systemic illness (n =20), clinically andhistopathologically diagnosed cases of leukoplakia (n=16) andoral submucous fibrosis (n=16) and oral squamous cellcarcinoma (n=35) respectively. 2ml blood was collected byvenipuncture from every subject after informed consent, serumwas separated and checked for fucose and fucosidase byspectrophotometric analysis.Results: The Normal value range of fucose is 8.3 to 9.5 mg/ dland that of fucosidase is 22.8 ± 7.1 U/L. There is an increasein the value range of fucose and fucosidase in the tissues ofpotentially malignant disorders and Squamous cell Carcinoma.
ABSTRACT
Introduction: -Oral candidiasis is an infection of oral cavity caused by an over growth of candida species. The proportions of yeast in the periodontal pockets are similar to some of periodontal bacteria, thus suggesting the possible role of Candida species in pathogenesis of periodontal pocket. The plant extract such as garlic and propolis, contain bioactive components which act against these organisms with no or less side effects than by the conventional antibiotics. Objectives: - To evaluate the efficacy of garlic and propolis extracts against candida albicans and compare it with Amphotericin-B as control at 3 different concentrations Methodology: - Subgingival plaque samples were collected and selectively cultivated for candida albicans. The antimicrobial activity of propolis and garlic was assessed and compared with Amphotericin-B. Conclusion: Garlic extract can be used as a potent agent in the eradication of candida albicans in chronic periodontitis patient.
ABSTRACT
Objetivo: Avaliar o conhecimento, atitudes e práticas de pais da cidade de Davangere, Índia, a respeito do cuidado com osdentes decíduos de seus filhos. Método: Mil questionários contendo aproximadamente 10 perguntas em dois idiomas Inglês e em dialeto local) foram distribuídos aos pais da cidade de Davangere, Índia. As respostas foram tabuladas e os resultados expressos por meioda distribuição de freqüência (absoluta e percentual). Resultados: A maioria dos pais não tinham consciência da importância dos dentes decíduos. Apenas 4% dos entrevistados tinham conhecimento sobre os dentes decíduos. Quando perguntados sobre a importância dos dentes decíduos, 82%dos pais disseram que esses elementos dentários não são importantes. Quanto à freqüência de escovação, a maioria(91,1%) dos pais relatou que eles solicitavam que os seus filhos escovassem os dentes uma única vez ao dia. Noventa vírgula seis por cento dos pais afirmaram que escolheriam os pediatras dos seus filhos. Apesar de trazerem os filhos ao cirurgião-dentista regularmente para consultas de rotina, muitos preferem não restaurá-los, mas deixá-los como estão (32%) e até mesmo extraí-los (61%).Conclusão: Verifica-se uma falta de conhecimento entre amaioria dos pais de Davangere, relativas aos cuidados com a dentição decídua de seus filhos. Deste modo, um alto nível deconsciência era obviamente desejável entre esses pais.
Objective: To assess the knowledge, attitude and practices of parents of Davangere city regarding the care of primary teeth. Methods: 1000 questionnaires containing about 10 questions written both in English and local language (Kannada) were prepared for data collection and were personally distributed to 1000 parents of Davangere city. Reponses obtained were tabulated and the results of the questionnaire were expressed as frequency distribution and computed in percentages. Results: Most of the parents were unaware of the importance of the primary teeth. Only 4% of parents had knowledge about primary teeth. When questioned about the importance of primary teeth, 82% of parents told that primary teeth are not important. For frequency of brushing, majority (91.1%) of parents reported that only once they ask their children to brush in a day. 90.6% parents stated that they would choose their child's paediatricians. Despite bringing their children to the dentist on a regular basis for check-ups, many would prefer not to have these teeth filled but would rather that they were left (32%) or even extracted (61%). Conclusion: There is a lack of knowledge in majority of parents of Davangere, pertaining to primary teeth care of their children. Thus, a high level of awareness was obviously desirable among these parents.
Subject(s)
Humans , Child , Tooth, Deciduous , Dental Care for Children , Parents/education , Oral Health , Data Interpretation, StatisticalABSTRACT
Supernumerary teeth are the teeth which are more in number in addition to the normal number found in either primary or permanent dentition. Paramolar is a supernumerary structure occurring buccally or lingually near the molars and it may be caused by combination of genetic and environmental factors. Reports of this unique entity are rarely found in the literature. The present article reports a case of paramolar in the maxillary molar region in an 11-year-old female patient and also reviews the literature about paramolar.