ABSTRACT
Introduction: Adiponectin and CTRP-3 as anti-inflammatory and hypoglycemic cytokines play an important role in the metabolic syndrome. The effects of aerobic training on both metabolic risk factors is unknown. Therefore we aimed to investigate the effects of aerobic training on and these cytokines serum adiponectin and Ctrp-3 levels in males with metabolic syndrome
Material and Methods: Twenty five males with metabolic syndrome [age: 56.04 +/- 4.37 yrs, weight:98.98 +/- 6.62 kg and BMI: 32.52 +/- 1.17 kg/m2] were randomized in two groups including the Aerobic Training [n=13] and the Controls [n=12]. Aerobic Training subjects were trained for eight weeks at 60-70% of max reserve heart rate, 3 sessions/wk. Blood samples were collected at baseline and 48 hrs following the last training session
Results: Aerobic Training increased serum adiponectin [P=0.002] and plasma HDL levels [P=0.001] and caused decreases in waist circumference [P=0.001], blood glucose [P=0.003] and insulin resistance [P=0.02]; however, there were no effects on serum CTRP-3 [P=0.30], insulin [P=0.65] and Mean atrial pressure [P=0.12] and plasma triglyceride levels [P=0.24]
Conclusion: Serum Adiponectin and CTRP-3 are associated with metabolic risk factors and insulin resistance and aerobic training can improve patients' metabolic state with synchronized elevation of the circulatory adiponectin level
ABSTRACT
Introduction: Lipocalin-2 as an adipokine expressed in adipose tissue has a direct relationship between systemic inflammation and insulin resistance in mice and humans. The aim of this study was to investigate the effect of progressive resistance training on serum lipocalin-2, non-HDL-c, and lipid and glycemic homeostasis in men
Materials and Methods: In this semi-experimental study, 20 healthy overweight and obese males [22.75 +/- 1.29 yr, 90.18 +/- 7.28 kg, 28.7 +/- 2.58 kg/m[2]] volunteered and were randomly assigned into the training [n=10] and the control [n=10] groups. Exercise protocol was progressive resistance training [8wk, 4d/wk, 60 min/d]. Blood samples were taken before and after exercise to evaluate serum variables. Elisa method was used to measure plasma lipocalin-2 concentration. The T-test and Pearson correlation was employed for data analysis
Results: After 8 weeks' progressive resistance training, no significant changes occurred in serum levels of lipocalin-2 [p=0.59] and blood glycaemia [p=0.53], although levels of non-HDL-c [p=0.024], triglycerides [p=0.017], total cholesterol [p=0.032] and systolic blood pressure [p=0.002] were significantly decreased. There were no significant changes in other variables. A significant positive correlation was observed between changes of lipocalin-2 with insulin resistance index and a significant negative correlation with WHR in the post exercise compared to before
Conclusion: The results of this study, confirm the relationship between the lipocalin-2 insulin resistance and central obesity [WHR], with no significant impact on lipocalin-2, although it led to a significant reduction in some serum lipid profiles
ABSTRACT
Eotaxin, which is an important chemokine in asthma, was recently reported to be increased in obesity in mice and humans. The purpose of this study was to investigate the effect of exercise training on plasma eotaxin levels, insulin resistance, maximal oxygen consumption [Vo2max] and some of the major physiological factors in overweight and obese adolescents. In this experimental study, 28 healthy obese and overweight male adolescents were randomly selected. We divided the obese subjects into two groups: exercise group [N = 13] and control group [N=15]. The exercise group performed combined exercise training, 4 days a week [70 min/d] for 8 weeks. Vo2max, adiposity, insulin resistance, lipid profile and eotaxin were measured before and after the completion of exercise training. Independent T-test and Pearson's correlation coefficient were used for data analysis. p<0.05 was considered significant. The results showed that 8 weeks of interval combined exercise training increased eotaxine level and Vo2max, and decreased insulin resistance, percentage of body fat, weight, BMI, WC, and plasma levels of triglycerides in obese male adolescents[P<0.05]. There was no significant relationship between primary level of eotaxine with other factors [P<0.05]. In spite of increased eotaxine level after 8 weeks of interval combined exercise training, We observed positive effects on some of the physiological indices [TG, %BF, insulin resistance, central obesity, BMI and Vo2max] in overweight and obese adolescents