ABSTRACT
Squamous cell carcinoma of the penis is rare, representing less than 1% of all adult cancers. The etiology of this cancer is still unknown, but many risk factors have been suggested, above all the human papilloma virus. The authors describe two cases of infiltrating penile tumors. The first patient presented with a glandular tumor of 5 cm which was treated by a distal penile amputation. The second patient had a ventrally located penile tumor associated with a urethral fistula. He was subjected to total penectomy with bilateral inguinal lymphadenectomy. Postoperatively, he developed lymphorrhea which resolved spontaneously. Surgery remains the treatment of choice for penile tumors and consists - depending on the case - of wide excision, partial or total penectomy with perineal urethrostomy