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1.
Maroc Medical. 2013; 35 (3): 171-175
in English | IMEMR | ID: emr-161700

ABSTRACT

The proliferative center of Aschoff, better known as radial scar, resembles carcinoma mammographically and histologically. It is a begnin conMucinous carcinoma of the eyelid is a rare tumor that usually occurs in the periorbital region. We propose a case of tumor affecting both eyelids on the same side. 55 year old man with swelling of the entire left lower eyelid, and a second swelling of the outer third of the upper eyelid evolving for over 5 years and has recurred after several incomplete excisions previously performed. A biopsy was performed with a result of mucinous carcinoma, The staging [CT orbitocerebrale, abdominal ultrasound, cervical ultrasound] did not reveal any other sites ormetastasis of the tumor. The patient was operated on in our department with complete resection of both tumors eyelid donating extemporaneous examinations obedient standards cancer surgery with rotation flaps and sliding. Primitive recurrent mucinous carcinoma of the eyelid is a rare malignancy tumor affecting the patients on their sixties. Clinically, it is in the form of an irregular nodular lesion on the eyelid, painless, with slow development, unaggressive. The evolution is characterized by frequent recurrences, sometimes late. Its diagnosis is histological. Treatment consists of complete excision of the tumor. Although it has a low metastatic potential, it has a high rate of recurrence

2.
Maroc Medical. 2012; 34 (4): 251-260
in French | IMEMR | ID: emr-151570

ABSTRACT

Prognosis for Acanthamoeba is worse than for many other types of infectious keratitis. Treatment is difficult especially in advanced stages and it may result in permanent visual impairment or blindness. However, especially if caught early, satisfactory outcomes can certainly be achieved. The purpose was to evaluate the clinical features in five patients diagnosed in our department between 2007 and 2011. Risk factors, clinical diagnosis and therapeutic characteristics were studied retrospectively in this study. All patients were referred in a second or third intention. These are three women and two men with a mean age of 38.5 years admitted for corneal abcess in 3 cases and pseudendritic keratitis in 2 others. The risk factors found were: contact lens wear in 2 cases, contact with contaminated water in 2 cases and the laboratory tests revealed an unrecognized diabetes in a case. Corneal sampling allowed the isolation of Acanthamoeba in 3 cases and in two cases the diagnosis was made by Polymerase Chain Reaction. All patients received broad-spectrum antibiotics and Hexamidine. ketoconazole was associated in 3 cases and Polyhexamethylene biguanide [PHMB] in 1 case. Evolution was marked by panophthalmitis and eyeball phthysis in 1 case, corneal opacity with neovascularization in two cases justifying a corneal graft. Regression with ad integrum recovery was observed in 2 cases of epithelial keratitis. The incidence of Acanthamoeba keratitis varies from one country to another between 0.15 and 1.4 per million inhabitants. Acanthamoeba are naturally occurring amoeba [tiny, one-celled animals] commonly found in water sources, such as tap water, well water, hot tubs, and soil and sewage systems. Contact lenses are still responsible for the majority of cases [2 cases] despite knowledge of this now well-established major risk factor and its preventive measures including strict hygiene for the maintenance of contact lenses. Medical treatment is very disappointing in advanced forms [3 cases]. The dramatic consequences of this complication justify a systematic treatment against amoeba in each case of suspected diagnosis. Acanthamoeba keratitis is a serious vision-threatening disease. Early diagnosis and treatment are essential for improving visual outcome

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