1.
JPAD-Journal of Pakistan Association of Dermatologists. 2011; 21 (3): 207-210
in English
| IMEMR
| ID: emr-137430
ABSTRACT
Extramammary Paget's disease [EMPD] is a rare neoplasm with only a limited number of reported cases in literature. It is mainly composed of intraepidermal Paget cells and possesses variable clinical behaviour and histological appearance leading to difficulty in diagnosis. We here report a case of primary EMPD in a 71-year-old male who presented with gradually progressive, pruritic, eczematous lesion in suprapubic region, not responding to topical medications. Histological assessment showed Paget cells infiltration throughout the epidermis with dermal invasion. Using immunohistochemistry, the expression of CK7, carcinoembryonic antigen [CEA] was examined to elucidate cellular differentiation of the carcinoma