Oculocutaneous albinism associated with axenfeld's anomaly: three case reports

Oculocutaneous albinism and anterior mesodermal dysgenesis are well-known heritable conditions, but their occurrence in association has only been rarely reported. We present cases of three siblings of a family with identical presentation suggesting that this association may be more than just a coincidence. This association is worth noting, as this could be one of the causes of ocular morbidity and poor vision in oculocutaneous albinism

retrospective study of fungal corneal ulcers in the south Sharqiyah region in Oman

To study the incidence, identify the risk factors and determine the predominant microorganisms and treatment regimen of fungal corneal ulcers. This was a retrospective analysis of corneal ulcers treated in the Ophthalmology Department of Sur Hospital, Oman, undertaken from January 2004 to December 2007. Medical and microbiology records of thirty two culture proven cases of fungal keratitis were reviewed for risk factors, laboratory findings and response to treatment. Out of the total 242 corneal ulcers, 13.22% were fungal. Among the 102 culture positive cases, 31.38% were fungal isolates. Fusarium spp [50%] and Aspergillus spp [34.4%] predominated in the hyaline fungal spectrum. The important risk factors were topical steroid usage in 31.25% of cases and ocular injury in 25%. The majority of cases [90.62%] responded to 2% ketoconazole alone or in combination with 0.15% amphotericin B. Fungal ulcer remains one of the leading causes of visual disability. Indiscriminate use of topical steroids and ocular trauma are the most important risk factors. Filamentous fungi are common aetiological agents in this region. Topical ketoconazole and amphotericin B were very effective for most of the cases

Juvenile myasthenia gravis: a case report

Myasthenia gravis most commonly affects young adult women and older men. Juvenile myasthenia gravis is considered to be a variant of adult myasthenia, and it comprises approximately 1% of all cases of myasthenia gravis. This report describes a ten-year old girl with drooping of eyelids since one year