ABSTRACT
Introduction: Eccrine spiradenoma is extremely rareadnexal tumor of the sweat gland, mainly affecting middleaged persons with equal incidence in males and females. Itis frequently a benign tumor characterized as solitary, painfuldeep - seated dermal nodule with most common sites being theupper thorax and face.Case report: A 35 year old male presented with multiple,painful swellings over scalp,face,anterior chest and backsince 6 months with loss of weight and appetite for 2 months.On examination, patient had a single cervical lymph node ofsize 1*1cm in the right posterior triangle of neck. Multipletender subcutaneous, hard, nonmobile swellings present overseveral areas with largest(2*1cm) over anterior chest wall.Histopathologically diagnosed as Eccrine spiradenoma whichrevealed clusters and sheets of cells having mild pleomorphicround to ovoid bland nuclei with indistinct cytoplasmicborders, occasional duct or follicular appearance and emptylooking lumina with no necrosis or mitotic activity.Conclusion: Eccrine spiradenoma, a rare benign adnexaltumor confirmed by histopathological examination.Differential diagnosis include, Neuroma, Dermatofibroma,Glomus tumor, Angiolipoma, Cylindromas and leiomyomas.Diagnosis confirmation by histopathological examination iscrucial because of its potential for malignant transformation.Its prognosis is poor as it has multiple recurrences.Histopathological examination is gold standard for thediagnosis.