ABSTRACT
Twelve cases of optic nerve glioma seen over a 28 year period are analysed herein in this autopsy study.
Subject(s)
Adolescent , Adult , Autopsy , Child , Child, Preschool , Fatal Outcome , Female , Glioma/pathology , Humans , Incidence , Male , Optic Nerve Neoplasms/pathology , Retrospective Studies , Tomography, X-Ray ComputedABSTRACT
Atypical Mesoblastic Nephroma (AMN) is a rare infantile renal tumour which may behave aggressively, in contrast to conventional Mesoblastic nephroma. During a 10 year period we encountered four cases of AMN. The mean age of presentation was three months. Size varied from 9-18 cms. All were soft and fleshy with a weight varying from 290-1200 gms. Three cases revealed cystic changes. Hemorrhage and necrosis was seen in all four cases. One case had associated Nephroblastomatosis Complex. The capsule and ureter were involved in one case each. Two of the four patients died of distant metastasis. Thus a close periodic follow up by non-invasive imaging techniques is indicated for early detection of recurrence and or metastasis in cases of AMN.
Subject(s)
Child, Preschool , Female , Humans , Infant , Kidney Neoplasms/congenital , Male , Nephroma, Mesoblastic/congenitalABSTRACT
A 50 year old female was found to have a lump on the right side of abdomen with discharging wound on the same side and was ultrasonographically diagnosed as renal cell carcinoma. On histopathology, it showed replacement of the kidney by mature adipose tissue renal replacement lipomatosis, along with pyelitis glandularis which is a rare condition.
Subject(s)
Female , Humans , Kidney Diseases/complications , Lipomatosis/complications , Middle Aged , Pyelitis/complicationsABSTRACT
Six cases of congenital leukemia were encountered in pediatric autopsies carried out over a period of 7 years. The postmortem findings of these cases were analysed and presented along with antemortem peripheral and bone marrow smear. All the cases were diagnosed as acute myeloid leukemia. Gross changes were observed in lungs, liver, spleen and kidneys. Histological abnormalities were detected in these organs as well as the heart, pancreas and intestine. Lymph node follicles were well preserved in all. The thymus showed a normal lobular pattern with interstitial infiltrate. Bone marrow showed myeloid blast cells with depletion of the erythroid and megakaryocytic cells.