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1.
Indian J Med Sci ; 1996 Oct; 50(10): 370-1
Article in English | IMSEAR | ID: sea-68854
2.
Indian J Lepr ; 1993 Oct-Dec; 65(4): 423-7
Article in English | IMSEAR | ID: sea-55138

ABSTRACT

A study was made on Langerhans cells (LC) in the dermal lesions of leprosy after epicutaneous application of 2:4 dinitrochlorobenzene (DNCB) to the lesion. LC were quantitated with OKT6 monoclonal antibody and indirect immunofluorescence. A depletion or reduction in the numbers of CD1+ epidermal LC was observed at both 4 and 24 hours after the application of DNCB in the lesions of both tuberculoid and lepromatous leprosy, compared to untreated lesions.


Subject(s)
Administration, Cutaneous , Antibodies, Monoclonal , Cell Count/drug effects , Dinitrochlorobenzene/therapeutic use , Humans , Langerhans Cells/drug effects , Leprosy, Lepromatous/drug therapy , Leprosy, Tuberculoid/drug therapy
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