ABSTRACT
Introduction@#According to the World Health Organization (WHO) in 2020, brain and central nervous system (CNS) cancers account for 2% of all newly diagnosed cancers in the world and 1.5% in Mongolia. Approximately 85-90% of all brain and other CNS tumors were diagnosed primary brain tumor. In 2019, the average 5 year survival probability was 50% for other cancers and 11% for the primary brain tumors. There were 28 patients with primary brain tumor and 33 relatively healthy individuals in our study. @*Goal@#To study the diagnostic value of serum aquaporin-4 and glial fibrous acidic protein in the diagnosis of primary brain cancer@*Material and Methods@#The Department of Neurosurgery at Third central hospital included 28 patients with primary brain cancer and 33 relatively healthy people. The study was conducted under the permission of the Medical Ethics Review Committee of the Ministry of Health on June 19, 2019 №119. Serum aquaporin-4 and glial fibrous acidic protein content was determined by the ELISA kits method using the human aquaporin-4 and glial fibrous acid protein test kit of the Chinese company “Sanlong”. The level is assumed to be true if the p value is less than 0.05.@*Results@#Mean age of the all participants was 42.9±16.5, 64% female and 36% male. Serum aquaporin-4 protein levels were 175.71±13.3 pg/ml and serum glial fibrilliary acidic protein levels were 2.682±0.218 ng/ml in patient with primary brain tumor. Serum aquaporin-4 protein and glial fibrilliary acidic protein levels were statistically significant high (p<0.001) in patient with primary brain tumor. Serum aquaporin-4 protein and glial fibrilliary acidic protein level differences were statistically significant (p<0.05) in benign and malignant tumor. There was no statistically significant correlation between serum aquaporin-4 and glial fibrillary acidic protein level and primary brain tumor grade.
ABSTRACT
Introduction@#Now days in case of two countries’ cooperation has been developing day by day, diversified activities such as collaboration and exchanging experience has been performing in health sector, medical science, besides pharmacology.@*Methods@#This study aimed to compare two countries’ pharmacist’s acquirements and roles and provide information to Mongolian Pharmaceutical Universities and pharmacist students. @*Pharmaceutical: Statistics @#</br> Population:</br> - 3 million in Mongolia</br> - 5 million in Korea</br> Number of pharmacists:</br> - 1726 (by 2016) in Mongolia </br> - 33182 (by 2016) in Korea</br> Number of Pharmaceutical Universities </br> - 7 universities, including 1 public and 6 private in Mongolia</br> - 34 universities, including 10 public and 25 private in Korea@*Results@#As a result of this study, pharmacist’s acquirements, role and working sectors of pharmacists in two countries are ordinarily same. There are some different sides below: </br> • Period of pharmacist’s preparatory training is 5 years at university in Mongolia and 2+4 years in Korea. </br> • Pharmaceutical Universities of Mongolia trains 2 specialists: pharmacist (bachelor`s degree) and pharmacist (diplom`s degree); College of Pharmacy of Korea trains pharmacist, pharmacist of traditional medicine and pharmaceutical engineering. </br> • For a role of business, in Mongolia pharmacist (diplom`s degree) is a separate specialist trained with diploma, whereas in Korea, if pharmacist gets a license, they have a right to compound a medicine legally, but commonly in pharmaceutical industry. </br> • As for sector, pharmacists are trained in many specializes, such as general pharmacist, clinical pharmacist, military pharmacist, nuclear pharmacist, cancer pharmacist and vet pharmacist. </br> • Special legal professional pharmacists work in Korea, such as governmental organization’s pharmacist, civil service pharmacist and public organization’s pharmacist. </br> • No person, other than pharmacists or oriental pharmacists may dispense drugs, and pharmacists or oriental pharmacists shall dispense drugs within the limit of the license, respectively: However, students who major in pharmacy at college may dispense drugs within the limits prescribed by Ordinance of the Ministry of Health and Welfare.