ABSTRACT
Objective To observe the clinical effect of atorvastatin calcium on carotid plaque in patients with cerebral infarction.Methods112 cases of arteriosclerosis in patients with cerebral infarction were randomLy selected from January 2015 to 2016 year in January in our hospital, according to digital method, divided into the observation group (n=56) and control group (n=56), the control group were treated with cinepazide treatment lasted 6 months, the observation group in the control group based on the use of atorvastatin calcium 20mg/d.For 6 months, clinical curative effect and compared two groups of patients with blood lipid levels and blood rheology indexes.ResultsThe total efficiency of the observation group was 89.28% higher than that of the control group (50/56) 69.65% (39/56);to compare the clinical efficacy of the two groups, the difference was statistically significant (P<0.05);the two groups of patients after treatment, blood rheology and blood lipid levels were significantly improved (P<0.05);and the observation group blood lipid levels and blood rheology the improvement is better than the control group (P<0.05).Conclusionatorvastatin can improve the metabolism of blood lipid, promote the circulation of cerebral blood flow, and has the function of resisting carotid atherosclerosis.
ABSTRACT
Objective To explore the clinical features,diagnosis and treatment of neurosyphilis.Methods The clinical data of 38 patients with neurosyphilis were analyzed.Results Among the 38 patients,2 cases were asymptomatic neurosyphilis,3 cases were syphilitic meningitis,16 cases were meningovascular syphilis,13 cases were paralytic dementia,and 4 cases were spinal tuberculosis.All 38 patients were positive in rapid plasma reagin test (RPRT),treponema pallidum hemagglutination assay (TPHA) of blood and TPHA of cerebrospinal fluid,32 cases (86.84％,33/38) were positive in RPRT of cerebrospinal fluid,and 5 cases (13.16％,5/38) were negative in RPRT of cerebrospinal fluid.All patients were improved in clinical symptom after treatment.RPRT of blood and cerebrospinal fluid were decreased but still positive,and the leukocyte and protein concentrations of cerebrospinal fluid were normal in 13 cases (34.21％,13/38).Six months after treatment,RPRT of blood and eerebrospinal fluid were negative in 17 cases (44.74％,17/38).The leukocyte and protein concentrations of cerebrospinal fluid were normal in 33 cases (86.84％,33/38).Conclusions Clinical manifestation of neurosyphilis is variety,and easily misdiagnosed.Syphilis examination in blood and cerebrospinal fluid is the necessary basis for diagnosis.Penicillin is the drug of first choice for the treatment.Cerebrospinal fluid leukocyte and protein concentrations are sensitive indicators to monitor the effect.