ABSTRACT
OBJECTIVE: To report the clinical spectrum of polyarteritis nodosa (PAN) from North India and highlight some unusual findings. DESIGN: Retrospective study. SETTING: Hospital based. SUBJECTS: Eight children with PAN. INTERVENTION: Treatment with prednisolone and cyclophosphamide. RESULTS: One child had spontaneous remission while another started deteriorating rapidly in spite of treatment and died within 2 weeks. Six children went into remission-of these one died, two were lost to follow-up and the remaining three are on regular follow-up for periods ranging from 3-5 years. CONCLUSIONS: Prednisolone and cyclophosphamide can significantly improve the outcome in childhood PAN.
Subject(s)
Child , Child, Preschool , Cyclophosphamide/therapeutic use , Female , Humans , Male , Polyarteritis Nodosa/drug therapy , Prednisolone/therapeutic use , Remission Induction , Remission, Spontaneous , Retrospective StudiesABSTRACT
A ten year old boy who died of the consequences of an infrequent gastrointestinal complication, whilst on induction chemotherapy for acute lymphatic leukemia, is being reported. Recent trends in the diagnosis and management of typhilitis or neutropenic enterocolitis have been reviewed.