1.
J Biosci
;
1993 Sept; 18(3): 303-309
Article
in English
| IMSEAR
| ID: sea-160943
ABSTRACT
Many studies indirectly indicate that the conformation of in vivo duplex DNA is the double helix. The most direct view, from the X-ray analysis of the nucleosome core particle, has also been interpreted in terms of the double helix structure. However, an alternative possibility exists; that the duplex adopts a metastable side-by-side conformation which readily converts to the double helix on removal of protein. Evidence for the existence of this conformation has been obtained from a reanalysis of the electron density map for the nucleosome particle.