ABSTRACT
Nuts are highly valued for their properties and are consumed worldwide owing to their health benefits, particularly, for the prevention and treatment of diseases, as well as a source of essential macro- and micronutrients. This study aimed to evaluate the effects of roasting on the nutritional value of nuts. Three types of nuts, raw and roasted almonds, cashews, and walnuts were selected from three well-known companies in Saudi Arabia. To analyze and evaluate the stability of macro- and micronutrients in nuts, modern separation and quantification methods, including inductively coupled plasma-optical emission spectrometry (ICP-OSE), were used to analyze and evaluate the stability of nutrients and heavy metals in nuts that are widely distributed and consumed. The results of this study indicate that nuts have high nutritional value and an inverse roasting effect. Comparing the nutrient and metal contents of raw and roasted nuts provides useful information on the nutritional science of nuts consumed by well-known manufacturers in the Kingdom of Saudi Arabia. Further investigations of nuts are needed to draw firm conclusions regarding their association with the prevention of many different diseases.
ABSTRACT
Inflammation may play a role in the pathogenesis of gestational diabetes mellitus (GDM) and also, it is one of the mostpopular pregnancy complications. The goal of the research was to study the association exists among common many formsin the stimulate area (-308G/A) of the TNF-alpha gene and increased danger for become better of GDM in Saudi pregnantwomen population.GDM and healthy subjects were genotyped with PCR- RFLP technique. No association was noticedamong the TNF-α -308 G/A in different and sensitivity to GDM disease in our Saudi cohort. There was a secondarycombination among TNF-α –308 G/A polymorphism in GDM (vs. normal control) (p = 0.605), which its triviality may becaused to survivor agent. The frequency of the -308 A allele (5) and genotype classification was in Hardy-Weinbergequilibrium (GG, n=54; GA, n=41; AA, n=5).The G-308A various, detected by PCR amplification and Nco-1 digestion,determines the lowest of a restriction site finding in a single band of 107 bp (the (A) allele). The (A) allele frequencies of the-308 (G/A) TNFα polymorphism were 26% in the GDM group and 29% in the depend subjects, with no significant differenceamong the two groups may be due to considerable variance in allele frequencies of the polymorphism by BMI quartiles (≥25kg/m2, for each quartile n=86) with -308G allele transporters had contains a higher BMI than A allele transporters(P=0.000**). Furthermore, considerable was found positively correlated with BMI, age, and children number.CONCLUSION: It could concluded that theTNF-α-308 G>A genotype frequency comparison among patients and controlwas not statistically significant in the Saudi women and also, the SNP in situation -308 (G/A) for the human. TNF- gene is adependent danger agent or a predictor for GDM.