Intracranial Glioblastoma Multiforme (Stage IV Glioma) Presenting as Papilledema: Two Case Reports.

Glioblastoma multiforme (GBM) is fast growing invasive gliomas often referred to as Grade IV glioma, arising from astrocyte spreading rapidly into nearby brain tissue and occur most commonly in temporal and frontal lobes. Here, we present case reports of two young female patients who presented to an eye hospital with predominant complaints of a headache and blurred vision, without any other neurological deficits. Comprehensive evaluation revealed intracranial frontal lobe mass lesion (GBM) causing severe papilledema and secondary optic atrophy.