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1.
Chongqing Medicine ; (36): 155-157, 2014.
Article in Chinese | WPRIM | ID: wpr-439898

ABSTRACT

Objective To study the occurrence site characteristics of middle cerebral artery aneurysm (MCAA ) in volume CT digital subtraction angiograhy(VCTDSA) .Methods The image characteristics in 72 cases of MCAA from May 2009 to January 2011 were retrospectively analyzed ,according to the running of middle cerebral artery ,the occurrence sites of aneurysm were divided into four categories :M1 segment ,M2 bifurcation ,M2 distal and M3-M5 segment ,the aneurysm number was conducted the statistics and the image characteristics were analyzed ;two neuroradiologists adopted the double-blind method to measure the MCAA angle in bifurcation of M2 segment and compared it with the bifurcation angle in the normal middle cerebral artery ,the difference between them were statistically analyzed .Results (1)M1 segment aneurysms were 7 cases(9 .70% ) ,M2 bifurcation aneurysms were 58 ca-ses(80 .56% ) ,M2 distal aneurysms were 5 cases(6 .94% ) and M3-M5 segment aneurysms were 2 cases(2 .78% ) .(2)The angle in M2 bifurcation of the normal middle cerebral artery was(99 .30 ± 22 .96)° ,M2 bifurcation aneurysm angle was(139 .26 ± 27 .61)° , the difference between them showing statistical significance (P0 .05) .(4)The M2 bifurcation angle in ruptured aneu-rysm was(133 .98 ± 30 .24)° ,which in unruptured aneurysms was(144 .53 ± 21 .81)° ,the difference between them had no statistical significance(P>0 .05) .Conclusion MCAA mainly occurred in M2 bifurcation .There is significant difference in M2 bifurcation an-gle between the aneurysm group and non-aneurysm group ,M2 bifurcation angle is increased ,the probability of aneurysm occurrence is increased .

2.
Chongqing Medicine ; (36): 1579-1580,1583, 2014.
Article in Chinese | WPRIM | ID: wpr-599061

ABSTRACT

Objective To investigar evaluate the value of anti-radiation with X-ray protective equipment for radiological interven-tion operation personnel.Methods Surveyed 60 cases of these operation staff during interventional operation in our hospital from October,2011 to October,2012,divided into the research group and the control group according to the physician protective habits, the research group was comprehensive protection with protective equipment including lead underwear,lead glass shield,lead cloth-ing,lead collar,lead the mask glasses radiation dose,the control group was partial protection with only employ lead clothes,lead col-lar,two groups were similar interventional operation on the same X-ray vessel machine,analysed the radiation dose of inside and outside the protective clothing changes and the blood picture for 2 groups personnel.Results The study group received radiation dose was significantly lower than the control group,the difference was statistically significant(P0.05).Conclusion The anti-radi-ation effect of X-ray protection equipment is remarkable for intervention operation personnel,should advocate the comprehensive personal radiation protection in the intervention operation period for the relative professionals persons.

3.
Journal of Southern Medical University ; (12): 1321-1324, 2013.
Article in Chinese | WPRIM | ID: wpr-319420

ABSTRACT

<p><b>OBJECTIVE</b>To test whether folic acid offers protection of the brain tissue against acute cerebral infarction in rats.</p><p><b>METHODS</b>Sprague-Dawley rats were divided into control (n=8), pre-treatment (n=12) and treatment (n=16) groups, all having routine feed for 7 days. The rats in the control and treatment groups were given normal saline daily, and those in the pre-treatment group received folic acid suspension daily. All the rats were then subject to middle cerebral artery occlusion (MCAO) for 24 h followed by reperfusion. On and after the operation day, the rats in the control group were given normal saline and those in the other two groups were given folic acid suspension daily. Neural function deficiency was evaluated on a daily basis after the operation, and on day 6 after the operation, brain biopsy was performed for examination with TTC staining. Monocyte chemokine -1 (MCP-1) in both normal and infarct tissues was measured by ELISA.</p><p><b>RESULTS</b>On day 6 after the operation, the neural function deficiency scores of the control, pre-treatment and treatment groups were 4.56∓3.63, 2.94∓2.94 and 1.00∓1.00, and the percentages of the infarct area (to the whole brain area) were (44.23∓10.06)%, (20.64∓6.78)% and (14.61∓13.51)%, respectively. The contents of MCP-1 in the infarct area of the brain tissues were 168.58∓107.21 ng/L, 152.91∓64.78 ng/L, and 97.74∓46.19 ng/L in the 3 groups, respectively.</p><p><b>CONCLUSION</b>Folic acid can protect brain tissue against acute cerebral infarction in rats.</p>


Subject(s)
Animals , Female , Rats , Cerebral Infarction , Drug Therapy , Folic Acid , Therapeutic Uses , Infarction, Middle Cerebral Artery , Drug Therapy , Neuroprotective Agents , Therapeutic Uses , Rats, Sprague-Dawley , Reperfusion Injury , Thrombolytic Therapy
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