ABSTRACT
Thirty cases of infective endocarditis identified in the autopsy of the University Hospital over a 10-year period are reviewed. The mean age of the patients was 30.6 years, and 70%) were below the age of 40 years. Sixty per cent of the cases had previous heart disease of which rheumatic heart disease was the most common. Degenerative heart disease and floppy mitral valve contributed one case each. The mitral valve was most commonly affected, and there were only 2 cases of right-sided endocarditis. Evidence of systemic embolization was present in 83% of the patients. The results of this stuy are compared with others from both developed and under-developed countries
Subject(s)
Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Endocarditis, Bacterial/epidemiology , Endocarditis, Bacterial/complications , Jamaica , Rheumatic Heart Disease/complications , Rheumatic Heart Disease/epidemiology , Age Factors , Hospitals, University , Developing CountriesABSTRACT
The in-vitro sensitivity to ampicillin, cotrimoxazole, nitrofuratoin, nalidixic acid and mecillinam was determined for 511 organisms isolated from 399 consecutive urine specimens. Urine specimens were divided into those of hospital in-patient origin (group A) and those from comunity patients(group B). Group B organisms were more sensitive than group A organisms. Over 75% of all group B organisms were sensitive to nitrofurantoin, nalidixic acid and mecillinam. Organisms resistant to multiple antibiotics were more frequently isolated from group A catheterized patients and are now less frequently isolated than in 1983. The antibiotic implications of these findings are discussed