Subject(s)
Adult , Anemia, Sickle Cell/complications , Homozygote , Humans , India , Male , Priapism/etiology , RecurrenceABSTRACT
A 31-year-old male patient with lepromatous leprosy developed fever, malaise, nausea, anorexia, lymphadenopathy, hepatitis, exfoliative dermatitis and ainhum like lesions while on multidrug therapy comprised of dapsone, clofazimine and rifampicin. The provocation tests confirmed the dapsone to be cause of this event.
Subject(s)
Adult , Clofazimine/therapeutic use , Dapsone/adverse effects , Dermatitis/chemically induced , Drug Therapy, Combination , Humans , Leprosy/drug therapy , Male , Rifampin/therapeutic useABSTRACT
The radiological bone changes have been studied in 50 patients comprising of lepromatous, tuberculoid, mixed (borderline lepromatous, borderline tuberculoid, dimorphous) and polyneuritic (neural) types of leprosy of which the former formed the largest group. The overall incidence of non-specific bone changes is higher as compared to specific bone changes. These were found to have highest incidence in the lepromatous type of leprosy, in the occupational group of manual workers and from 3rd to 6th decade of life. With the longer duration of the disease, the incidence of non-specific bone changes is also more.