ABSTRACT
Objective: to investigate the relationship between waist circumference and cecal intubation time [CIT] in female subjects during colonoscopy
Study Design: a descriptive study
Place and Duration of Study: department of General Surgery, Kanuni Training and Research Hospital, Turkey, from January to September 2016
Methodology: this study included 61 female subjects who underwent colonoscopy in our clinic. The colonoscopies were performed by a single surgeon. The waist circumferences of all subjects were measured before the procedure with the technique recommended by the WHO. In colonoscopy, the cecal intubation time was recorded for each subject. The results were evaluated statistically and p <0.05 was considered significant
Results: the mean waist circumference was 100.6 +/- 19.0 cm. The mean cecal intubation time was 9.0 +/- 2.7 minutes. A strong statistically significant negative correlation was found between waist circumference and cecal intubation time [r = -0.689, p <0.001]
Conclusion: the cecal intubation time was found to be significantly shorter in the female subjects with larger waist circumferences
ABSTRACT
Objective: to create acute pancreatitis condition experimentally in rats using cerulein, and to reveal histopathological effects in pancreatic tissue with erdosteine
Study Design: an experimental study
Place and Duration of Study: department of General Surgery, Duzce University, Turkey, from June to October 2014
Methodology: thirty male Wistar albino rats were divided into three groups. No procedures were applied to Group 1. The rats in Group 2 and Group 3 were injected cerulein, to establish an experimental pancreatitis model and the blood amylase and lipase values were examined. The rats in Group 3 were given 10 mg/kg erdosteine. This treatment was continued for another 2 days and the rats were sacrificed. The pancreatic tissues were examined histopathologically for edema, inflammation, acinar necrosis, fat necrosis, and vacuolization
Results: the lipase and amylase values and the histopathological examination of pancreatic tissues evidenced that the experimental acute pancreatitis model was established and edema, inflammation, acinar necrosis, fat necrosis, and vacuolization were observed in the pancreatic tissues. The statistical results suggest that erdosteine can decrease the edema, inflammation, acinar necrosis, fat necrosis and vacuolization scores in the tissues
Conclusion: the severity of acute pancreatitis, induced by cerulein in rats, is reduced with the use of erdosteine